Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM033712-10
Application #
2177107
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1984-12-01
Project End
1999-11-30
Budget Start
1995-12-11
Budget End
1996-11-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Sinha, Prem Kumar; Castro-Guerrero, Norma; Patki, Gaurav et al. (2015) Conserved amino acid residues of the NuoD segment important for structure and function of Escherichia coli NDH-1 (complex I). Biochemistry 54:753-64
Sato, Motoaki; Torres-Bacete, Jesus; Sinha, Prem Kumar et al. (2014) Essential regions in the membrane domain of bacterial complex I (NDH-1): the machinery for proton translocation. J Bioenerg Biomembr 46:279-87
Barker, Clive S; Meshcheryakova, Irina V; Sasaki, Toshio et al. (2014) Randomly selected suppressor mutations in genes for NADH?:?quinone oxidoreductase-1, which rescue motility of a Salmonella ubiquinone-biosynthesis mutant strain. Microbiology 160:1075-86
Sato, Motoaki; Sinha, Prem Kumar; Torres-Bacete, Jesus et al. (2013) Energy transducing roles of antiporter-like subunits in Escherichia coli NDH-1 with main focus on subunit NuoN (ND2). J Biol Chem 288:24705-16
Torres-Bacete, Jesus; Sinha, Prem Kumar; Sato, Motoaki et al. (2012) Roles of subunit NuoK (ND4L) in the energy-transducing mechanism of Escherichia coli NDH-1 (NADH:quinone oxidoreductase). J Biol Chem 287:42763-72
Iwata, Momi; Lee, Yang; Yamashita, Tetsuo et al. (2012) The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates. Proc Natl Acad Sci U S A 109:15247-52
Sinha, Prem Kumar; Nakamaru-Ogiso, Eiko; Torres-Bacete, Jesus et al. (2012) Electron transfer in subunit NuoI (TYKY) of Escherichia coli NADH:quinone oxidoreductase (NDH-1). J Biol Chem 287:17363-73
Yang, Yu; Yamashita, Tetsuo; Nakamaru-Ogiso, Eiko et al. (2011) Reaction mechanism of single subunit NADH-ubiquinone oxidoreductase (Ndi1) from Saccharomyces cerevisiae: evidence for a ternary complex mechanism. J Biol Chem 286:9287-97
Torres-Bacete, Jesus; Sinha, Prem Kumar; Matsuno-Yagi, Akemi et al. (2011) Structural contribution of C-terminal segments of NuoL (ND5) and NuoM (ND4) subunits of complex I from Escherichia coli. J Biol Chem 286:34007-14
Murai, Masatoshi; Yamashita, Tetsuo; Senoh, Mai et al. (2010) Characterization of the ubiquinone binding site in the alternative NADH-quinone oxidoreductase of Saccharomyces cerevisiae by photoaffinity labeling. Biochemistry 49:2973-80

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