Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM034028-13
Application #
2177272
Study Section
Special Emphasis Panel (ZRG2-GEN (05))
Project Start
1984-07-01
Project End
2000-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Ambros, Victor; Ruvkun, Gary (2018) Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs. Genetics 209:651-673
McJunkin, Katherine; Ambros, Victor (2017) A microRNA family exerts maternal control on sex determination in C. elegans. Genes Dev 31:422-437
Ren, Zhiji; Veksler-Lublinsky, Isana; Morrissey, David et al. (2016) Staufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans. G3 (Bethesda) 6:1227-37
Burke, Samantha L; Hammell, Molly; Ambros, Victor (2015) Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS in Caenorhabditis elegans. Genetics 200:1201-18
Ren, Zhiji; Ambros, Victor R (2015) Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress. Proc Natl Acad Sci U S A 112:E2366-75
Sterling, Catherine H; Veksler-Lublinsky, Isana; Ambros, Victor (2015) An efficient and sensitive method for preparing cDNA libraries from scarce biological samples. Nucleic Acids Res 43:e1
Zinovyeva, Anna Y; Veksler-Lublinsky, Isana; Vashisht, Ajay A et al. (2015) Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Proc Natl Acad Sci U S A 112:E5271-80
Harandi, Omid F; Ambros, Victor R (2015) Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans. Proc Natl Acad Sci U S A 112:E287-96
Nelson, Charles; Ambros, Victor; Baehrecke, Eric H (2014) miR-14 regulates autophagy during developmental cell death by targeting ip3-kinase 2. Mol Cell 56:376-88
Zinovyeva, Anna Y; Bouasker, Samir; Simard, Martin J et al. (2014) Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression. PLoS Genet 10:e1004286

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