Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM034534-15
Application #
2177480
Study Section
Virology Study Section (VR)
Project Start
1989-09-01
Project End
1997-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Genetics
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Tsvitov, Marianna; Frampton Jr, Arthur R; Shah, Waris A et al. (2007) Characterization of soluble glycoprotein D-mediated herpes simplex virus type 1 infection. Virology 360:477-91
Hong, C-S; Goins, W F; Goss, J R et al. (2006) Herpes simplex virus RNAi and neprilysin gene transfer vectors reduce accumulation of Alzheimer's disease-related amyloid-beta peptide in vivo. Gene Ther 13:1068-79
Jiang, Canping; Ataai, Mohammad; Ozuer, Ali et al. (2006) Inactivation of herpes simplex type 1 gene vector on immobilized metal affinity chromatography: oxidative damage by hydroxyl free radicals and its prevention. Biotechnol Bioeng 95:48-57
Jiang, Canping; Glorioso, Joseph C; Ataai, Mohammad (2006) Presence of imidazole in loading buffer prevents formation of free radical in immobilized metal affinity chromatography and dramatically improves the recovery of herpes simplex virus type 1 gene therapy vectors. J Chromatogr A 1121:40-5
Nakano, Kenji; Asano, Ryutaro; Tsumoto, Kouhei et al. (2005) Herpes simplex virus targeting to the EGF receptor by a gD-specific soluble bridging molecule. Mol Ther 11:617-26
Moriuchi, Shusuke; Glorioso, Joseph C; Maruno, Motohiko et al. (2005) Combination gene therapy for glioblastoma involving herpes simplex virus vector-mediated codelivery of mutant IkappaBalpha and HSV thymidine kinase. Cancer Gene Ther 12:487-96
Sasaki, Katsumi; Chancellor, Michael B; Goins, William F et al. (2004) Gene therapy using replication-defective herpes simplex virus vectors expressing nerve growth factor in a rat model of diabetic cystopathy. Diabetes 53:2723-30
Niranjan, Ajay; Wolfe, Darren; Tamura, Masakazu et al. (2003) Treatment of rat gliosarcoma brain tumors by HSV-based multigene therapy combined with radiosurgery. Mol Ther 8:530-42
Burton, Edward A; Hong, Chang-Sook; Glorioso, Joseph C (2003) The stable 2.0-kilobase intron of the herpes simplex virus type 1 latency-associated transcript does not function as an antisense repressor of ICP0 in nonneuronal cells. J Virol 77:3516-30
Moriuchi, S; Wolfe, D; Tamura, M et al. (2002) Double suicide gene therapy using a replication defective herpes simplex virus vector reveals reciprocal interference in a malignant glioma model. Gene Ther 9:584-91

Showing the most recent 10 out of 46 publications