Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM034558-13
Application #
2177498
Study Section
Biochemistry Study Section (BIO)
Project Start
1984-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Kumar, Rupesh; Grosbart, Ma?gorzata; Nurse, Pearl et al. (2017) The bacterial condensin MukB compacts DNA by sequestering supercoils and stabilizing topologically isolated loops. J Biol Chem 292:16904-16920
Kumar, Rupesh; Nurse, Pearl; Bahng, Soon et al. (2017) The MukB-topoisomerase IV interaction is required for proper chromosome compaction. J Biol Chem 292:16921-16932
Chang, Elizabeth; Pourmal, Sergei; Zhou, Chun et al. (2016) N-Terminal Amino Acid Sequence Determination of Proteins by N-Terminal Dimethyl Labeling: Pitfalls and Advantages When Compared with Edman Degradation Sequence Analysis. J Biomol Tech 27:61-74
Bahng, Soon; Hayama, Ryo; Marians, Kenneth J (2016) MukB-mediated Catenation of DNA Is ATP and MukEF Independent. J Biol Chem 291:23999-24008
Nurse, Pearl; Marians, Kenneth J (2013) Purification and characterization of Escherichia coli MreB protein. J Biol Chem 288:3469-75
Hayama, Ryo; Bahng, Soon; Karasu, Mehmet E et al. (2013) The MukB-ParC interaction affects the intramolecular, not intermolecular, activities of topoisomerase IV. J Biol Chem 288:7653-61
Lee, Chong; Marians, Kenneth J (2013) Characterization of the nucleoid-associated protein YejK. J Biol Chem 288:31503-16
Perez-Cheeks, Brenda A; Lee, Chong; Hayama, Ryo et al. (2012) A role for topoisomerase III in Escherichia coli chromosome segregation. Mol Microbiol 86:1007-22
Hayama, Ryo; Marians, Kenneth J (2010) Physical and functional interaction between the condensin MukB and the decatenase topoisomerase IV in Escherichia coli. Proc Natl Acad Sci U S A 107:18826-31
Bigot, Sarah; Marians, Kenneth J (2010) DNA chirality-dependent stimulation of topoisomerase IV activity by the C-terminal AAA+ domain of FtsK. Nucleic Acids Res 38:3031-40

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