|
Hale, S P; Poole, L B; Gerlt, J A (1993) Mechanism of the reaction catalyzed by staphylococcal nuclease: identification of the rate-determining step. Biochemistry 32:7479-87
|
|
Gerlt, J A; Gassman, P G (1993) Understanding the rates of certain enzyme-catalyzed reactions: proton abstraction from carbon acids, acyl-transfer reactions, and displacement reactions of phosphodiesters. Biochemistry 32:11943-52
|
|
Baldisseri, D M; Torchia, D A; Poole, L B et al. (1991) Deletion of the omega-loop in the active site of staphylococcal nuclease. 2. Effects on protein structure and dynamics. Biochemistry 30:3628-33
|
|
Poole, L B; Loveys, D A; Hale, S P et al. (1991) Deletion of the omega-loop in the active site of staphylococcal nuclease. 1. Effect on catalysis and stability. Biochemistry 30:3621-7
|
|
Pourmotabbed, T; Dell'Acqua, M; Gerlt, J A et al. (1990) Kinetic and conformational effects of lysine substitutions for arginines 35 and 87 in the active site of staphylococcal nuclease. Biochemistry 29:3677-83
|
|
Wilde, J A; Bolton, P H; Hibler, D W et al. (1989) Isotopic labeling with hydrogen-2 and carbon-13 to compare conformations of proteins and mutants generated by site-directed mutagenesis, II. Methods Enzymol 177:282-92
|
|
Serpersu, E H; Hibler, D W; Gerlt, J A et al. (1989) Kinetic and magnetic resonance studies of the glutamate-43 to serine mutant of staphylococcal nuclease. Biochemistry 28:1539-48
|
|
Wilde, J A; Bolton, P H; Dell'Acqua, M et al. (1988) Identification of residues involved in a conformational change accompanying substitutions for glutamate-43 in staphylococcal nuclease. Biochemistry 27:4127-32
|
|
Hibler, D W; Stolowich, N J; Reynolds, M A et al. (1987) Site-directed mutants of staphylococcal nuclease. Detection and localization by 1H NMR spectroscopy of conformational changes accompanying substitutions for glutamic acid-43. Biochemistry 26:6278-86
|
|
Calderon, R O; Stolowich, N J; Gerlt, J A et al. (1985) Thermal denaturation of staphylococcal nuclease. Biochemistry 24:6044-9
|
