Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM034622-12
Application #
2177521
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1985-04-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Long, David T; Kreuzer, Kenneth N (2009) Fork regression is an active helicase-driven pathway in bacteriophage T4. EMBO Rep 10:394-9
Pohlhaus, Jennifer Reineke; Kreuzer, Kenneth N (2006) Formation and processing of stalled replication forks--utility of two-dimensional agarose gels. Methods Enzymol 409:477-93
Kreuzer, Kenneth N (2005) Interplay between DNA replication and recombination in prokaryotes. Annu Rev Microbiol 59:43-67
Dudas, K C; Kreuzer, K N (2001) UvsW protein regulates bacteriophage T4 origin-dependent replication by unwinding R-loops. Mol Cell Biol 21:2706-15
Doan, P L; Belanger, K G; Kreuzer, K N (2001) Two types of recombination hotspots in bacteriophage T4: one requires DNA damage and a replication origin and the other does not. Genetics 157:1077-87
George, J W; Stohr, B A; Tomso, D J et al. (2001) The tight linkage between DNA replication and double-strand break repair in bacteriophage T4. Proc Natl Acad Sci U S A 98:8290-7
Nossal, N G; Dudas, K C; Kreuzer, K N (2001) Bacteriophage T4 proteins replicate plasmids with a preformed R loop at the T4 ori(uvsY) replication origin in vitro. Mol Cell 7:31-41
Cicero, M P; Sharp, M M; Gross, C A et al. (2001) Substitutions in bacteriophage T4 AsiA and Escherichia coli sigma(70) that suppress T4 motA activation mutations. J Bacteriol 183:2289-97
Jones, C E; Mueser, T C; Dudas, K C et al. (2001) Bacteriophage T4 gene 41 helicase and gene 59 helicase-loading protein: a versatile couple with roles in replication and recombination. Proc Natl Acad Sci U S A 98:8312-8
Kreuzer, K N (2000) Recombination-dependent DNA replication in phage T4. Trends Biochem Sci 25:165-73

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