Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM036214-10
Application #
2178220
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1986-04-04
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Massachusetts Medical School Worcester
Department
Surgery
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655

  Publications

Bandyopadhyay, Gautam; Bandyopadhyay, Sanjukta; Bankey, Paul E et al. (2014) Elevated postinjury thrombospondin 1-CD47 triggering aids differentiation of patients' defective inflammatory CD1a+dendritic cells. J Leukoc Biol 96:797-807
Bandyopadhyay, Gautam; Bankey, Paul E; Miller-Graziano, Carol L (2012) Trauma patients' elevated tumor necrosis related apoptosis inducing ligand (TRAIL) contributes to increased T cell apoptosis. Clin Immunol 145:44-54
Bankey, Paul E; Banerjee, Sanjib; Zucchiatti, Andrea et al. (2010) Cytokine induced expression of programmed death ligands in human neutrophils. Immunol Lett 129:100-7
Kotz, Kenneth T; Xiao, Wenzong; Miller-Graziano, Carol et al. (2010) Clinical microfluidics for neutrophil genomics and proteomics. Nat Med 16:1042-7
Miller-Graziano, Carol L; De, Asit; Laudanski, Krzysztof et al. (2008) HSP27: an anti-inflammatory and immunomodulatory stress protein acting to dampen immune function. Novartis Found Symp 291:196-208;discussion 208-11, 221-
Laudanski, Krzysztof; De, Asit; Miller-Graziano, Carol (2007) Exogenous heat shock protein 27 uniquely blocks differentiation of monocytes to dendritic cells. Eur J Immunol 37:2812-24
Laudanski, Krzysztof; De, Asit; Pellegrini, Joanmarie et al. (2006) Simultaneous aberrations in Mphi and T cell function adversely affect trauma patients' clinical outcome: a possible faulty IL-13 feedback loop. Clin Immunol 118:332-41
Laudanski, Krzysztof; De, Asit; Brouxhon, Sabine et al. (2004) Abnormal PGE(2) regulation of monocyte TNF-alpha levels in trauma patients parallels development of a more macrophage-like phenotype. Shock 22:204-12
De, Asit K; Laudanski, Krzysztof; Miller-Graziano, Carol L (2003) Failure of monocytes of trauma patients to convert to immature dendritic cells is related to preferential macrophage-colony-stimulating factor-driven macrophage differentiation. J Immunol 170:6355-62
De, A K; Kodys, K M; Yeh, B S et al. (2000) Exaggerated human monocyte IL-10 concomitant to minimal TNF-alpha induction by heat-shock protein 27 (Hsp27) suggests Hsp27 is primarily an antiinflammatory stimulus. J Immunol 165:3951-8

Showing the most recent 10 out of 29 publications