Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM036605-11
Application #
2178456
Study Section
Virology Study Section (VR)
Project Start
1986-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
161202122
City
Irvine
State
CA
Country
United States
Zip Code
92697
Villarreal, L P; Defilippis, V R; Gottlieb, K A (2000) Acute and persistent viral life strategies and their relationship to emerging diseases. Virology 272:6-Jan
Gottlieb, K; Villarreal, L P (2000) The distribution and kinetics of polyomavirus in lungs of intranasally infected newborn mice. Virology 266:52-65
Piatti, P G; Gottlieb, K A; Taylor, J A et al. (1998) Approaches to study interactions between small DNA viruses and differentiated tissue. Methods 16:62-82
You, Z; Villarreal, L P (1996) Mapping of polyomavirus DNA replicative intermediates by two-dimensional gel analysis using chemiluminescent detection. J Virol Methods 56:173-8
Atencio, I A; Belli, B; Hobbs, M et al. (1995) A model for mixed virus disease: co-infection with Moloney murine leukemia virus potentiates runting induced by polyomavirus (A2 strain) in Balb/c and NIH Swiss mice. Virology 212:356-66
Shadan, F F; Villarreal, L P (1995) The evolution of small DNA viruses of eukaryotes: past and present considerations. Virus Genes 11:239-57
Atencio, I A; Meraz, A; Villarreal, L P (1994) The secretory cells of mouse salivary glands are nonpermissive for polyomavirus replication. Virology 200:842-8
Atencio, I A; Villarreal, L P (1994) Polyomavirus replicates in differentiating but not in proliferating tubules of adult mouse polycystic kidneys. Virology 201:26-35
Shadan, F F; Cowsert, L M; Villarreal, L P (1994) n-Butyrate, a cell cycle blocker, inhibits the replication of polyomaviruses and papillomaviruses but not that of adenoviruses and herpesviruses. J Virol 68:4785-96
Atencio, I A; Shadan, F F; Zhou, X J et al. (1993) Adult mouse kidneys become permissive to acute polyomavirus infection and reactivate persistent infections in response to cellular damage and regeneration. J Virol 67:1424-32

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