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Chen, Ligong; Shu, Yan; Liang, Xiaomin et al. (2014) OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. Proc Natl Acad Sci U S A 111:9983-8
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Yee, Sook Wah; Chen, Ligong; Giacomini, Kathleen M (2012) The role of ATM in response to metformin treatment and activation of AMPK. Nat Genet 44:359-60
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Minematsu, Tsuyoshi; Giacomini, Kathleen M (2011) Interactions of tyrosine kinase inhibitors with organic cation transporters and multidrug and toxic compound extrusion proteins. Mol Cancer Ther 10:531-9
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Li, Shuanglian; Chen, Ying; Zhang, Shuzhong et al. (2011) Role of organic cation transporter 1, OCT1 in the pharmacokinetics and toxicity of cis-diammine(pyridine)chloroplatinum(II) and oxaliplatin in mice. Pharm Res 28:610-25
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Choi, J H; Yee, S W; Ramirez, A H et al. (2011) A common 5'-UTR variant in MATE2-K is associated with poor response to metformin. Clin Pharmacol Ther 90:674-84
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More, Swati S; Itsara, Melissa; Yang, Xiaodong et al. (2011) Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems. Clin Cancer Res 17:2339-49
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Kido, Yasuto; Matsson, Pär; Giacomini, Kathleen M (2011) Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. J Med Chem 54:4548-58
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More, Swati S; Akil, Omar; Ianculescu, Alexandra G et al. (2010) Role of the copper transporter, CTR1, in platinum-induced ototoxicity. J Neurosci 30:9500-9
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Ianculescu, Alexandra G; Friesema, Edith C H; Visser, Theo J et al. (2010) Transport of thyroid hormones is selectively inhibited by 3-iodothyronamine. Mol Biosyst 6:1403-10
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Chen, Ligong; Takizawa, Miho; Chen, Eugene et al. (2010) Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function. J Pharmacol Exp Ther 335:42-50
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