Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM037005-11
Application #
2022115
Study Section
Biochemistry Study Section (BIO)
Project Start
1986-07-01
Project End
1997-11-30
Budget Start
1996-09-01
Budget End
1997-11-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Bukhman, Y V; Draper, D E (1997) Affinities and selectivities of divalent cation binding sites within an RNA tertiary structure. J Mol Biol 273:1020-31
Gluick, T C; Gerstner, R B; Draper, D E (1997) Effects of Mg2+, K+, and H+ on an equilibrium between alternative conformations of an RNA pseudoknot. J Mol Biol 270:451-63
Gluick, T C; Wills, N M; Gesteland, R F et al. (1997) Folding of an mRNA pseudoknot required for stop codon readthrough: effects of mono- and divalent ions on stability. Biochemistry 36:16173-86
Draper, D E (1996) Strategies for RNA folding. Trends Biochem Sci 21:145-9
Gluick, T C; Gerstner, R B; Draper, D E (1995) A conformational switch in a regulated mRNA involves tertiary structure. Nucleic Acids Symp Ser :200-2
Kebbekus, P; Draper, D E; Hagerman, P (1995) Persistence length of RNA. Biochemistry 34:4354-7
Morse, S E; Draper, D E (1995) Purine-purine mismatches in RNA helices: evidence for protonated G.A pairs and next-nearest neighbor effects. Nucleic Acids Res 23:302-6
Draper, D E; Gluick, T C (1995) Melting studies of RNA unfolding and RNA-ligand interactions. Methods Enzymol 259:281-305
Gluick, T C; Draper, D E (1994) Thermodynamics of folding a pseudoknotted mRNA fragment. J Mol Biol 241:246-62
Tang, R S; Draper, D E (1994) Bend and helical twist associated with a symmetric internal loop from 5S ribosomal RNA. Biochemistry 33:10089-93

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