Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM037254-10
Application #
2178745
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1986-07-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Hartman, Elon; Wang, Zhonghua; Zhang, Qi et al. (2013) Intrinsic dynamics of an extended hydrophobic core in the S. cerevisiae RNase III dsRBD contributes to recognition of specific RNA binding sites. J Mol Biol 425:546-62
Wang, Zhonghua; Hartman, Elon; Roy, Kevin et al. (2011) Structure of a yeast RNase III dsRBD complex with a noncanonical RNA substrate provides new insights into binding specificity of dsRBDs. Structure 19:999-1010
Koo, Bon-Kyung; Park, Chin-Ju; Fernandez, Cesar F et al. (2011) Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface. J Mol Biol 411:927-42
Kim, Nak-Kyoon; Theimer, Carla A; Mitchell, James R et al. (2010) Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA. Nucleic Acids Res 38:6746-56
Singh, Mahavir; Gonzales, Fernando A; Cascio, Duilio et al. (2009) Structure and functional studies of the CS domain of the essential H/ACA ribonucleoparticle assembly protein SHQ1. J Biol Chem 284:1906-16
Kim, Nak-Kyoon; Zhang, Qi; Zhou, Jing et al. (2008) Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA. J Mol Biol 384:1249-61
Wu, Haihong; Feigon, Juli (2007) H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification. Proc Natl Acad Sci U S A 104:6655-60
Khanna, May; Wu, Haihong; Johansson, Carina et al. (2006) Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA. RNA 12:40-52
Qin, Peter Z; Feigon, Juli; Hubbell, Wayne L (2005) Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg(2+)-dependent docking of a GAAA tetraloop. J Mol Biol 351:1-8
Wu, Haihong; Finger, L David; Feigon, Juli (2005) Structure determination of protein/RNA complexes by NMR. Methods Enzymol 394:525-45

Showing the most recent 10 out of 54 publications