Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM038341-09
Application #
2179300
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1986-12-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Missouri Kansas City
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
800772162
City
Kansas City
State
MO
Country
United States
Zip Code
64110

  Publications

Berezov, Alan; McNeill, Megan J; Iriarte, Ana et al. (2005) Electron paramagnetic resonance and fluorescence studies of the conformation of aspartate aminotransferase bound to GroEL. Protein J 24:465-78
Oses-Prieto, Juan A; Bengoechea-Alonso, Maria T; Artigues, Antonio et al. (2003) The nature of the rate-limiting steps in the refolding of the cofactor-dependent protein aspartate aminotransferase. J Biol Chem 278:49988-99
Wu, Ting-Huai; Oses-Prieto, Juan A; Iriarte, Ana et al. (2003) Release of pyridoxal 5'-phosphate upon unfolding of mitochondrial aspartate aminotransferase. Biochim Biophys Acta 1647:315-20
Cooper, Arthur J L; Bruschi, Sam A; Iriarte, Ana et al. (2002) Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions. Biochem J 368:253-61
Artigues, Antonio; Iriarte, Ana; Martinez-Carrion, Marino (2002) Binding to chaperones allows import of a purified mitochondrial precursor into mitochondria. J Biol Chem 277:25047-55
Donate, F; Yanez, A J; Iriarte, A et al. (2000) Interaction of the precursor to mitochondrial aspartate aminotransferase and its presequence peptide with model membranes. J Biol Chem 275:34147-56
Mattingly Jr, J R; Yanez, A J; Martinez-Carrion, M (2000) The folding of nascent mitochondrial aspartate aminotransferase synthesized in a cell-free extract can be assisted by GroEL and GroES. Arch Biochem Biophys 382:113-22
Scherrer, S; Iriarte, A; Martinez-Carrion, M (2000) Stability and release requirements of the complexes of GroEL with two homologous mammalian aminotransferases. J Protein Chem 19:591-602
Artigues, A; Crawford, D L; Iriarte, A et al. (1998) Divergent Hsc70 binding properties of mitochondrial and cytosolic aspartate aminotransferase. Implications for their segregation to different cellular compartments. J Biol Chem 273:33130-4
Torella, C; Mattingly Jr, J R; Artigues, A et al. (1998) Insight into the conformation of protein folding intermediate(s) trapped by GroEL. J Biol Chem 273:3915-25

Showing the most recent 10 out of 27 publications