Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM038545-05S1
Application #
3295051
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1987-07-01
Project End
1993-06-30
Budget Start
1992-06-01
Budget End
1992-06-30
Support Year
5
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Lu, Hua; Fermaintt, Charles S; Cherepanova, Natalia A et al. (2018) Mammalian STT3A/B oligosaccharyltransferases segregate N-glycosylation at the translocon from lipid-linked oligosaccharide hydrolysis. Proc Natl Acad Sci U S A 115:9557-9562
Lopez-Sambrooks, Cecilia; Shrimal, Shiteshu; Khodier, Carol et al. (2016) Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nat Chem Biol 12:1023-1030
DeRossi, Charles; Vacaru, Ana; Rafiq, Ruhina et al. (2016) trappc11 is required for protein glycosylation in zebrafish and humans. Mol Biol Cell 27:1220-34
Hasan, Maroof; Fermaintt, Charles S; Gao, Ningguo et al. (2015) Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation. Immunity 43:463-74
Leclerc, Guy J; DeSalvo, Joanna; Du, Jianfeng et al. (2015) Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress. Leuk Res :
Lehrman, Mark A (2015) Flipping a Lipid-Linked Oligosaccharide? You Must Whip It! Trends Biochem Sci 40:715-717
Philips, Katherine B; Kurtoglu, Metin; Leung, Howard J et al. (2014) Increased sensitivity to glucose starvation correlates with downregulation of glycogen phosphorylase isoform PYGB in tumor cell lines resistant to 2-deoxy-D-glucose. Cancer Chemother Pharmacol 73:349-61
Wang, Zhao V; Deng, Yingfeng; Gao, Ningguo et al. (2014) Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway. Cell 156:1179-1192
Chu, Jaime; Mir, Alexander; Gao, Ningguo et al. (2013) A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation. Dis Model Mech 6:95-105
Gao, Ningguo; Holmes, Justin; Lehrman, Mark A (2013) Letter to the Glycoforum: Improved protocols for preparing lipid-linked and related saccharides for Fluorophore-Assisted Carbohydrate Electrophoresis (FACE). Glycobiology 23:1111

Showing the most recent 10 out of 67 publications