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Langston, Lance; O'Donnell, Mike (2017) Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase. Elife 6:
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Georgescu, Roxana; Langston, Lance; O'Donnell, Mike (2015) A proposal: Evolution of PCNA's role as a marker of newly replicated DNA. DNA Repair (Amst) 29:4-15
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Georgescu, Roxana E; Schauer, Grant D; Yao, Nina Y et al. (2015) Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation. Elife 4:e04988
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Sun, Jingchuan; Shi, Yi; Georgescu, Roxana E et al. (2015) The architecture of a eukaryotic replisome. Nat Struct Mol Biol 22:976-82
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Langston, Lance D; Zhang, Dan; Yurieva, Olga et al. (2014) CMG helicase and DNA polymerase ? form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication. Proc Natl Acad Sci U S A 111:15390-5
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Marzahn, Melissa R; Hayner, Jaclyn N; Finkelstein, Jeff et al. (2014) The ATP sites of AAA+ clamp loaders work together as a switch to assemble clamps on DNA. J Biol Chem 289:5537-48
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Georgescu, Roxana E; Yao, Nina; Indiani, Chiara et al. (2014) Replisome mechanics: lagging strand events that influence speed and processivity. Nucleic Acids Res 42:6497-510
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Georgescu, Roxana E; Langston, Lance; Yao, Nina Y et al. (2014) Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork. Nat Struct Mol Biol 21:664-70
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Indiani, Chiara; O'Donnell, Mike (2013) A proposal: Source of single strand DNA that elicits the SOS response. Front Biosci (Landmark Ed) 18:312-23
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Pomerantz, Richard T; Goodman, Myron F; O'Donnell, Michael E (2013) DNA polymerases are error-prone at RecA-mediated recombination intermediates. Cell Cycle 12:2558-63
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