Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM039561-08
Application #
2179922
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1988-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Pharmacology
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Rorabaugh, Boyd R; Chakravarti, Bandana; Mabe, Nathaniel W et al. (2017) Regulator of G Protein Signaling 6 Protects the Heart from Ischemic Injury. J Pharmacol Exp Ther 360:409-416
Feng, Huijie; Sjögren, Benita; Karaj, Behirda et al. (2017) Movement disorder in GNAO1 encephalopathy associated with gain-of-function mutations. Neurology 89:762-770
Evelyn, Chris R; Lisabeth, Erika M; Wade, Susan M et al. (2016) Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks. Microarrays (Basel) 5:
Sjögren, Benita; Parra, Sergio; Atkins, Kevin B et al. (2016) Digoxin-Mediated Upregulation of RGS2 Protein Protects against Cardiac Injury. J Pharmacol Exp Ther 357:311-9
Blazer, Levi L; Storaska, Andrew J; Jutkiewicz, Emily M et al. (2015) Selectivity and anti-Parkinson's potential of thiadiazolidinone RGS4 inhibitors. ACS Chem Neurosci 6:911-9
Parra, Sergio; Huang, Xinyan; Charbeneau, Raelene A et al. (2014) Conditional disruption of interactions between G?i2 and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury. BMC Pharmacol Toxicol 15:29
Lamberts, Jennifer T; Smith, Chelsea E; Li, Ming-Hua et al. (2013) Differential control of opioid antinociception to thermal stimuli in a knock-in mouse expressing regulator of G-protein signaling-insensitive G?o protein. J Neurosci 33:4369-77
Kaur, Kuljeet; Parra, Sergio; Chen, Rong et al. (2012) G?i2 signaling: friend or foe in cardiac injury and heart failure? Naunyn Schmiedebergs Arch Pharmacol 385:443-53
Waterson, Rachael E; Thompson, Corbin G; Mabe, Nathaniel W et al. (2011) G?(i2)-mediated protection from ischaemic injury is modulated by endogenous RGS proteins in the mouse heart. Cardiovasc Res 91:45-52
Sjogren, Benita; Neubig, Richard R (2010) Thinking outside of the ""RGS box"": new approaches to therapeutic targeting of regulators of G protein signaling. Mol Pharmacol 78:550-7

Showing the most recent 10 out of 29 publications