Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM040505-14
Application #
6617871
Study Section
Biochemistry Study Section (BIO)
Program Officer
Tompkins, Laurie
Project Start
1988-07-01
Project End
2005-08-31
Budget Start
2003-09-01
Budget End
2004-08-31
Support Year
14
Fiscal Year
2003
Total Cost
$346,500
Indirect Cost
Name
Duke University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Bartkowiak, Bartlomiej; Greenleaf, Arno L (2015) Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex. J Biol Chem 290:1786-95
Bartkowiak, Bartlomiej; Yan, Christopher; Greenleaf, Arno L (2015) Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas. Biochim Biophys Acta 1849:1179-87
Liu, Jiangxin; Fan, Shilong; Lee, Chul-Jin et al. (2013) Specific interaction of the transcription elongation regulator TCERG1 with RNA polymerase II requires simultaneous phosphorylation at Ser2, Ser5, and Ser7 within the carboxyl-terminal domain repeat. J Biol Chem 288:10890-901
Winsor, Tiffany Sabin; Bartkowiak, Bartlomiej; Bennett, Craig B et al. (2013) A DNA damage response system associated with the phosphoCTD of elongating RNA polymerase II. PLoS One 8:e60909
Möller, André; Xie, Sheila Q; Hosp, Fabian et al. (2012) Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease. Mol Cell Proteomics 11:M111.011767
Bartkowiak, Bartlomiej; Greenleaf, Arno L (2011) Phosphorylation of RNAPII: To P-TEFb or not to P-TEFb? Transcription 2:115-119
MacKellar, April L; Greenleaf, Arno L (2011) Cotranscriptional association of mRNA export factor Yra1 with C-terminal domain of RNA polymerase II. J Biol Chem 286:36385-95
Werner-Allen, Jon W; Lee, Chul-Jin; Liu, Pengda et al. (2011) cis-Proline-mediated Ser(P)5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72. J Biol Chem 286:5717-26
Bartkowiak, Bartlomiej; Mackellar, April L; Greenleaf, Arno L (2011) Updating the CTD Story: From Tail to Epic. Genet Res Int 2011:623718
Liu, Pengda; Kenney, John M; Stiller, John W et al. (2010) Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain. Mol Biol Evol 27:2628-41

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