Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM041883-07
Application #
2181102
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1989-06-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Cristina, Landeta; McPartland, Laura; Tran, Ngoc Q et al. (2018) Inhibition of Pseudomonas aeruginosa and Mycobacterium tuberculosis disulfide bond forming enzymes. Mol Microbiol :
Meehan, Brian M; Landeta, Cristina; Boyd, Dana et al. (2017) The essential cell division protein FtsN contains a critical disulfide bond in a non-essential domain. Mol Microbiol 103:413-422
Landeta, Cristina; Meehan, Brian M; McPartland, Laura et al. (2017) Inhibition of virulence-promoting disulfide bond formation enzyme DsbB is blocked by mutating residues in two distinct regions. J Biol Chem 292:6529-6541
Chatelle, Claire; Kraemer, Stéphanie; Ren, Guoping et al. (2015) Converting a Sulfenic Acid Reductase into a Disulfide Bond Isomerase. Antioxid Redox Signal 23:945-57
Williamson, Jessica A; Cho, Seung-Hyun; Ye, Jiqing et al. (2015) Structure and multistate function of the transmembrane electron transporter CcdA. Nat Struct Mol Biol 22:809-14
Hatahet, Feras; Blazyk, Jessica L; Martineau, Eugenie et al. (2015) Altered Escherichia coli membrane protein assembly machinery allows proper membrane assembly of eukaryotic protein vitamin K epoxide reductase. Proc Natl Acad Sci U S A 112:15184-9
Hatahet, Feras; Boyd, Dana; Beckwith, Jon (2014) Disulfide bond formation in prokaryotes: history, diversity and design. Biochim Biophys Acta 1844:1402-14
Dwyer, Robert S; Malinverni, Juliana C; Boyd, Dana et al. (2014) Folding LacZ in the periplasm of Escherichia coli. J Bacteriol 196:3343-50
Beckwith, Jon (2014) Mission possible: getting to yes with François Jacob. Res Microbiol 165:348-50
Li, Zaoping; Boyd, Dana; Reindl, Martin et al. (2014) Identification of YidC residues that define interactions with the Sec Apparatus. J Bacteriol 196:367-77

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