Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM042219-03S1
Application #
3300744
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1989-07-01
Project End
1994-06-30
Budget Start
1992-06-01
Budget End
1992-06-30
Support Year
3
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Wang, Yuanguo; Wang, Shaohui; Bouillaut, Laurent et al. (2018) Oral Immunization with Nontoxigenic Clostridium difficile Strains Expressing Chimeric Fragments of TcdA and TcdB Elicits Protective Immunity against C. difficile Infection in Both Mice and Hamsters. Infect Immun 86:
King, Alyssa N; Borkar, Samiksha; Samuels, David J et al. (2018) Guanine limitation results in CodY-dependent and -independent alteration of Staphylococcus aureus physiology and gene expression. J Bacteriol :
Rothstein, David M; Lazinski, David; Osburne, Marcia S et al. (2017) A Mutation in the Bacillus subtilis rsbU Gene That Limits RNA Synthesis during Sporulation. J Bacteriol 199:
Levdikov, Vladimir M; Blagova, Elena; Young, Vicki L et al. (2017) Structure of the Branched-chain Amino Acid and GTP-sensing Global Regulator, CodY, from Bacillus subtilis. J Biol Chem 292:2714-2728
Samuels, David J; Wang, Zhe; Rhee, Kyu Y et al. (2017) A Tandem Liquid Chromatography-Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus. J Vis Exp :
McAllister, Kathleen N; Bouillaut, Laurent; Kahn, Jennifer N et al. (2017) Using CRISPR-Cas9-mediated genome editing to generate C. difficile mutants defective in selenoproteins synthesis. Sci Rep 7:14672
Dubois, Thomas; Dancer-Thibonnier, Marie; Monot, Marc et al. (2016) Control of Clostridium difficile Physiopathology in Response to Cysteine Availability. Infect Immun 84:2389-405
Barbieri, Giulia; Albertini, Alessandra M; Ferrari, Eugenio et al. (2016) Interplay of CodY and ScoC in the Regulation of Major Extracellular Protease Genes of Bacillus subtilis. J Bacteriol 198:907-20
Nawrocki, Kathryn L; Edwards, Adrianne N; Daou, Nadine et al. (2016) CodY-Dependent Regulation of Sporulation in Clostridium difficile. J Bacteriol 198:2113-30
Waters, Nicholas R; Samuels, David J; Behera, Ranjan K et al. (2016) A spectrum of CodY activities drives metabolic reorganization and virulence gene expression in Staphylococcus aureus. Mol Microbiol 101:495-514

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