Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM042561-08
Application #
2181482
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1989-07-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Chemistry
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Kharytonchyk, Siarhei; Brown, Joshua D; Stilger, Krista et al. (2018) Influence of gag and RRE Sequences on HIV-1 RNA Packaging Signal Structure and Function. J Mol Biol 430:2066-2079
Zhang, Kaiming; Keane, Sarah C; Su, Zhaoming et al. (2018) Structure of the 30 kDa HIV-1 RNA Dimerization Signal by a Hybrid Cryo-EM, NMR, and Molecular Dynamics Approach. Structure 26:490-498.e3
Gaines, Christy R; Tkacik, Emre; Rivera-Oven, Amalia et al. (2018) HIV-1 Matrix Protein Interactions with tRNA: Implications for Membrane Targeting. J Mol Biol 430:2113-2127
Marchant, Jan; Bax, Ad; Summers, Michael F (2018) Accurate Measurement of Residual Dipolar Couplings in Large RNAs by Variable Flip Angle NMR. J Am Chem Soc 140:6978-6983
Keane, Sarah C; Van, Verna; Frank, Heather M et al. (2016) NMR detection of intermolecular interaction sites in the dimeric 5'-leader of the HIV-1 genome. Proc Natl Acad Sci U S A 113:13033-13038
Keane, Sarah C; Summers, Michael F (2016) NMR Studies of the Structure and Function of the HIV-1 5'-Leader. Viruses 8:
Kharytonchyk, Siarhei; Monti, Sarah; Smaldino, Philip J et al. (2016) Transcriptional start site heterogeneity modulates the structure and function of the HIV-1 genome. Proc Natl Acad Sci U S A 113:13378-13383
Keane, Sarah C; Heng, Xiao; Lu, Kun et al. (2015) RNA structure. Structure of the HIV-1 RNA packaging signal. Science 348:917-21
Brown, Joshua D; Summers, Michael F; Johnson, Bruce A (2015) Prediction of hydrogen and carbon chemical shifts from RNA using database mining and support vector regression. J Biomol NMR 63:39-52
Tran, Thao; Liu, Yuanyuan; Marchant, Jan et al. (2015) Conserved determinants of lentiviral genome dimerization. Retrovirology 12:83

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