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Ojima, Iwao; Kumar, Kunal; Awasthi, Divya et al. (2014) Drug discovery targeting cell division proteins, microtubules and FtsZ. Bioorg Med Chem 22:5060-77
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Seitz, Joshua; Vineberg, Jacob G; Zuniga, Edison S et al. (2013) Fluorine-Containing Taxoid Anticancer Agents and Their Tumor-Targeted Drug Delivery. J Fluor Chem 152:157-165
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Ojima, Iwao (2013) Exploration of fluorine chemistry at the multidisciplinary interface of chemistry and biology. J Org Chem 78:6358-83
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Kamath, Anushree; Ojima, Iwao (2012) Advances in the chemistry of ?-lactam and its medicinal applications. Tetrahedron 68:10640-10664
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Sun, Liang; Veith, Jean M; Pera, Paula et al. (2010) Design and synthesis of de novo cytotoxic alkaloids by mimicking the bioactive conformation of paclitaxel. Bioorg Med Chem 18:7101-12
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Sun, Liang; Simmerling, Carlos; Ojima, Iwao (2009) Recent advances in the study of the bioactive conformation of taxol. ChemMedChem 4:719-31
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Sun, Liang; Geng, Xudong; Geney, Raphael et al. (2008) Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids. J Org Chem 73:9584-93
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Ojima, Iwao; Chen, Jin; Sun, Liang et al. (2008) Design, synthesis, and biological evaluation of new-generation taxoids. J Med Chem 51:3203-21
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Geney, Raphael; Sun, Liang; Pera, Paula et al. (2005) Use of the tubulin bound paclitaxel conformation for structure-based rational drug design. Chem Biol 12:339-48
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Minderman, Hans; Brooks, Tracy A; O'Loughlin, Kieran L et al. (2004) Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023. Cancer Chemother Pharmacol 53:363-9
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Showing the most recent 10 out of 24 publications
