Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM043237-04S1
Application #
3302236
Study Section
Biochemistry Study Section (BIO)
Project Start
1990-07-01
Project End
1995-06-30
Budget Start
1992-07-01
Budget End
1993-06-30
Support Year
4
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
North Carolina State University Raleigh
Department
Type
Schools of Earth Sciences/Natur
DUNS #
City
Raleigh
State
NC
Country
United States
Zip Code
27695

  Publications

Huggins, Wayne; Ghosh, Sujit K; Nanda, Kavita et al. (2005) Internucleotide movements during formation of 16 S rRNA-rRNA photocrosslinks and their connection to the 30 S subunit conformational dynamics. J Mol Biol 354:358-74
Nanda, Kavita; Wollenzien, Paul (2004) Pattern of 4-thiouridine-induced cross-linking in 16S ribosomal RNA in the Escherichia coli 30S subunit. Biochemistry 43:8923-34
Huggins, Wayne; Wollenzien, Paul (2004) A 16S rRNA-tRNA product containing a nucleotide phototrimer and specific for tRNA in the P/E hybrid state in the Escherichia coli ribosome. Nucleic Acids Res 32:6548-56
Shapkina, Tatjana; Lappi, Simon; Franzen, Stefan et al. (2004) Efficiency and pattern of UV pulse laser-induced RNA-RNA cross-linking in the ribosome. Nucleic Acids Res 32:1518-26
Noah, James W; Shapkina, Tatjana G; Nanda, Kavita et al. (2003) Conformational change in the 16S rRNA in the Escherichia coli 70S ribosome induced by P/P- and P/E-site tRNAPhe binding. Biochemistry 42:14386-96
Zhirnov, Oksana V; Wollenzien, Paul (2003) Action spectra for UV-light induced RNA-RNA crosslinking in 16S ribosomal RNA in the ribosome. Photochem Photobiol Sci 2:688-93
Dolan, M A; Babin, P; Wollenzien, P (2001) Construction and analysis of base-paired regions of the 16S rRNA in the 30S ribosomal subunit determined by constraint satisfaction molecular modelling. J Mol Graph Model 19:495-513
Juzumiene, D I; Wollenzien, P (2001) Arrangement of the central pseudoknot region of 16S rRNA in the 30S ribosomal subunit determined by site-directed 4-thiouridine crosslinking. RNA 7:71-84
Juzumiene, D; Shapkina, T; Kirillov, S et al. (2001) Short-range RNA-RNA crosslinking methods to determine rRNA structure and interactions. Methods 25:333-43
Noah, J W; Shapkina, T; Wollenzien, P (2000) UV-induced crosslinks in the 16S rRNAs of Escherichia coli, Bacillus subtilis and Thermus aquaticus and their implications for ribosome structure and photochemistry. Nucleic Acids Res 28:3785-92

Showing the most recent 10 out of 26 publications