Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM043340-06
Application #
2181971
Study Section
Metallobiochemistry Study Section (BMT)
Project Start
1991-01-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Chemistry
Type
Other Domestic Higher Education
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027
Stirnemann, Guillaume; Kang, Seung-gu; Zhou, Ruhong et al. (2014) How force unfolding differs from chemical denaturation. Proc Natl Acad Sci U S A 111:3413-8
Mondal, Jagannath; Stirnemann, Guillaume; Berne, B J (2013) When does trimethylamine N-oxide fold a polymer chain and urea unfold it? J Phys Chem B 117:8723-32
Mondal, Jagannath; Morrone, Joseph A; Berne, B J (2013) How hydrophobic drying forces impact the kinetics of molecular recognition. Proc Natl Acad Sci U S A 110:13277-82
Stirnemann, Guillaume; Giganti, David; Fernandez, Julio M et al. (2013) Elasticity, structure, and relaxation of extended proteins under force. Proc Natl Acad Sci U S A 110:3847-52
Wang, Lingle; Berne, B J; Friesner, Richard A (2012) On achieving high accuracy and reliability in the calculation of relative protein-ligand binding affinities. Proc Natl Acad Sci U S A 109:1937-42
Wang, Lingle; Berne, B J; Friesner, R A (2011) Ligand binding to protein-binding pockets with wet and dry regions. Proc Natl Acad Sci U S A 108:1326-30
Wang, Lingle; Friesner, Richard A; Berne, B J (2011) Replica exchange with solute scaling: a more efficient version of replica exchange with solute tempering (REST2). J Phys Chem B 115:9431-8
Zhou, Ruhong; Li, Jingyuan; Hua, Lan et al. (2011) Comment on ""urea-mediated protein denaturation: a consensus view"". J Phys Chem B 115:1323-6; discussion 1327-8
Li, Jingyuan; Fernandez, Julio M; Berne, B J (2010) Water's role in the force-induced unfolding of ubiquitin. Proc Natl Acad Sci U S A 107:19284-9
Young, Tom; Hua, Lan; Huang, Xuhui et al. (2010) Dewetting transitions in protein cavities. Proteins 78:1856-69

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