Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM048435-03
Application #
2185892
Study Section
Molecular Biology Study Section (MBY)
Project Start
1994-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109
Budde, Mark W; Roth, Mark B (2010) Hydrogen sulfide increases hypoxia-inducible factor-1 activity independently of von Hippel-Lindau tumor suppressor-1 in C. elegans. Mol Biol Cell 21:212-7
Chan, Kin; Goldmark, Jesse P; Roth, Mark B (2010) Suspended animation extends survival limits of Caenorhabditis elegans and Saccharomyces cerevisiae at low temperature. Mol Biol Cell 21:2161-71
Miller, Dana L; Roth, Mark B (2009) C. elegans are protected from lethal hypoxia by an embryonic diapause. Curr Biol 19:1233-7
Frazier 3rd, Harold N; Roth, Mark B (2009) Adaptive sugar provisioning controls survival of C. elegans embryos in adverse environments. Curr Biol 19:859-63
Chan, Kin; Roth, Mark B (2008) Anoxia-induced suspended animation in budding yeast as an experimental paradigm for studying oxygen-regulated gene expression. Eukaryot Cell 7:1795-808
Miller, Dana L; Roth, Mark B (2007) Hydrogen sulfide increases thermotolerance and lifespan in Caenorhabditis elegans. Proc Natl Acad Sci U S A 104:20618-22
Moore, Landon L; Stanvitch, Gerald; Roth, Mark B et al. (2005) HCP-4/CENP-C promotes the prophase timing of centromere resolution by enabling the centromere association of HCP-6 in Caenorhabditis elegans. Mol Cell Biol 25:2583-92
Blackstone, Eric; Morrison, Mike; Roth, Mark B (2005) H2S induces a suspended animation-like state in mice. Science 308:518
Nystul, Todd G; Roth, Mark B (2004) Carbon monoxide-induced suspended animation protects against hypoxic damage in Caenorhabditis elegans. Proc Natl Acad Sci U S A 101:9133-6
Stear, Jeffrey H; Roth, Mark B (2004) The Caenorhabditis elegans kinetochore reorganizes at prometaphase and in response to checkpoint stimuli. Mol Biol Cell 15:5187-96

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