Cofactor Dependent Amine Oxidations

Sayre, Lawrence M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 2R01GM048812-04
• Application #: 2186331
• Study Section: Special Emphasis Panel (ZRG3-BNP (02))
• Project Start: 1993-07-01
• Project End: 2000-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: Case Western Reserve University
• Department: Chemistry
• Type: Schools of Arts and Sciences
• DUNS #: 077758407
• City: Cleveland
• State: OH
• Country: United States
• Zip Code: 44106

Publications

Kim, Jisook; Lee, Irene N (2017) Inactivation of bovine plasma amine oxidase by 1,1,1-trihalo-3-aminopropanes. Bioorg Chem 75:265-273

Ling, Ke-Qing; Sayre, Lawrence M (2009) Discovery of a sensitive, selective, and tightly binding fluorogenic substrate of bovine plasma amine oxidase. J Org Chem 74:339-50

Ling, Ke-Qing; Li, Wen-Shan; Sayre, Lawrence M (2008) Oxidations of N-(3-indoleethyl) cyclic aliphatic amines by horseradish peroxidase: the indole ring binds to the enzyme and mediates electron-transfer amine oxidation. J Am Chem Soc 130:933-44

Chun, J; Kent, U M; Moss, R M et al. (2000) Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2-phenyl-2-(1-piperidinyl)propane. Drug Metab Dispos 28:905-11