Mechanism of Initiation by RNA Polymerase II

Gralla, Jay D.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 5R01GM049048-03
• Application #: 2186575
• Study Section: Molecular Biology Study Section (MBY)
• Project Start: 1994-05-01
• Project End: 1998-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of California Los Angeles
• Department: Chemistry
• Type: Schools of Arts and Sciences
• DUNS #: 119132785
• City: Los Angeles
• State: CA
• Country: United States
• Zip Code: 90095

Publications

Tran, Khiem; Gralla, Jay D (2010) The TFIIB tip domain couples transcription initiation to events involved in RNA processing. J Biol Chem 285:39580-7

Tran, Khiem; Gralla, Jay D (2008) Control of the timing of promoter escape and RNA catalysis by the transcription factor IIb fingertip. J Biol Chem 283:15665-71

Wolner, B S; Gralla, J D (1997) Promoter activation via a cyclic AMP response element in vitro. J Biol Chem 272:32301-7

Chang, C; Gralla, J D (1994) A critical role for chromatin in mounting a synergistic transcriptional response to GAL4-VP16. Mol Cell Biol 14:5175-81

Jiang, Y; Gralla, J D (1994) RNA polymerase II phosphorylation: uncoupling from GAL4-VP16 directed open complex formation and transcription in a reconstituted system. Nucleic Acids Res 22:4958-62

Jiang, Y; Triezenberg, S J; Gralla, J D (1994) Defective transcriptional activation by diverse VP16 mutants associated with a common inability to form open promoter complexes. J Biol Chem 269:5505-8