Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM049825-04
Application #
2187368
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1993-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1998-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Iowa
Department
Physiology
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Khakhina, Svetlana; Simonicova, Lucia; Moye-Rowley, W Scott (2018) Positive autoregulation and repression of transactivation are key regulatory features of the Candida glabrata Pdr1 transcription factor. Mol Microbiol 107:747-764
Balzi, Elisabetta; Moye-Rowley, W Scott (2018) Unveiling the transcriptional control of pleiotropic drug resistance in Saccharomyces cerevisiae: Contributions of André Goffeau and his group. Yeast :
Moye-Rowley, W Scott (2018) Multiple interfaces control activity of the Candida glabrata Pdr1 transcription factor mediating azole drug resistance. Curr Genet :
Paul, Sanjoy; Diekema, Daniel; Moye-Rowley, W Scott (2017) Contributions of both ATP-Binding Cassette Transporter and Cyp51A Proteins Are Essential for Azole Resistance in Aspergillus fumigatus. Antimicrob Agents Chemother 61:
Hagiwara, Daisuke; Miura, Daisuke; Shimizu, Kiminori et al. (2017) A Novel Zn2-Cys6 Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions. PLoS Pathog 13:e1006096
Khakhina, Svetlana; Johnson, Soraya S; Manoharlal, Raman et al. (2015) Control of Plasma Membrane Permeability by ABC Transporters. Eukaryot Cell 14:442-53
Paul, Sanjoy; Doering, Tamara L; Moye-Rowley, W Scott (2015) Cryptococcus neoformans Yap1 is required for normal fluconazole and oxidative stress resistance. Fungal Genet Biol 74:1-9
Moye-Rowley, W S (2015) Multiple mechanisms contribute to the development of clinically significant azole resistance in Aspergillus fumigatus. Front Microbiol 6:70
Paul, Sanjoy; Bair, Thomas B; Moye-Rowley, W Scott (2014) Identification of genomic binding sites for Candida glabrata Pdr1 transcription factor in wild-type and ?0 cells. Antimicrob Agents Chemother 58:6904-12
Paul, Sanjoy; Moye-Rowley, W Scott (2014) Multidrug resistance in fungi: regulation of transporter-encoding gene expression. Front Physiol 5:143

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