Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM050016-04
Application #
2187601
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1993-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Robinett, Natalie G; Peterson, Ryan L; Culotta, Valeria C (2018) Eukaryotic copper-only superoxide dismutases (SODs): A new class of SOD enzymes and SOD-like protein domains. J Biol Chem 293:4636-4643
Broxton, Chynna N; He, Bixi; Bruno, Vincent M et al. (2018) A role for Candida albicans superoxide dismutase enzymes in glucose signaling. Biochem Biophys Res Commun 495:814-820
Schatzman, Sabrina S; Culotta, Valeria C (2018) Chemical Warfare at the Microorganismal Level: A Closer Look at the Superoxide Dismutase Enzymes of Pathogens. ACS Infect Dis 4:893-903
Rossi, Diego C P; Gleason, Julie E; Sanchez, Hiram et al. (2017) Candida albicans FRE8 encodes a member of the NADPH oxidase family that produces a burst of ROS during fungal morphogenesis. PLoS Pathog 13:e1006763
Broxton, Chynna N; Culotta, Valeria C (2016) SOD Enzymes and Microbial Pathogens: Surviving the Oxidative Storm of Infection. PLoS Pathog 12:e1005295
Besold, Angelique N; Culbertson, Edward M; Culotta, Valeria C (2016) The Yin and Yang of copper during infection. J Biol Inorg Chem 21:137-44
Peterson, Ryan L; Galaleldeen, Ahmad; Villarreal, Johanna et al. (2016) The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases. J Biol Chem 291:20911-20923
Baron, J Allen; Chen, Janice S; Culotta, Valeria C (2015) Cu/Zn superoxide dismutase and the proton ATPase Pma1p of Saccharomyces cerevisiae. Biochem Biophys Res Commun 462:251-6
Li, Cissy X; Gleason, Julie E; Zhang, Sean X et al. (2015) Candida albicans adapts to host copper during infection by swapping metal cofactors for superoxide dismutase. Proc Natl Acad Sci U S A 112:E5336-42
Gleason, Julie E; Li, Cissy X; Odeh, Hana M et al. (2014) Species-specific activation of Cu/Zn SOD by its CCS copper chaperone in the pathogenic yeast Candida albicans. J Biol Inorg Chem 19:595-603

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