Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
7R01GM050526-04
Application #
2415213
Study Section
Molecular Biology Study Section (MBY)
Project Start
1994-08-01
Project End
1998-07-31
Budget Start
1997-01-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Type
Organized Research Units
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Andrews, Alex M; McCartney, Heather J; Errington, Tim M et al. (2018) A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links. Nat Commun 9:2592
Rodriguez-Boulan, Enrique; Macara, Ian G (2014) Organization and execution of the epithelial polarity programme. Nat Rev Mol Cell Biol 15:225-42
Petkowski, Janusz J; Bonsignore, Lindsay A; Tooley, John G et al. (2013) NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1. Biochem J 456:453-62
Errington, Timothy M; Macara, Ian G (2013) Depletion of the adaptor protein NCK increases UV-induced p53 phosphorylation and promotes apoptosis. PLoS One 8:e76204
Bailey, Aaron O; Panchenko, Tanya; Sathyan, Kizhakke M et al. (2013) Posttranslational modification of CENP-A influences the conformation of centromeric chromatin. Proc Natl Acad Sci U S A 110:11827-32
Petkowski, Janusz J; Schaner Tooley, Christine E; Anderson, Lissa C et al. (2012) Substrate specificity of mammalian N-terminal ?-amino methyltransferase NRMT. Biochemistry 51:5942-50
Tooley, Christine E Schaner; Petkowski, Janusz J; Muratore-Schroeder, Tara L et al. (2010) NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein. Nature 466:1125-8
Eisinger-Mathason, T S Karin; Andrade, Josefa; Groehler, Angela L et al. (2008) Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival. Mol Cell 31:722-36
Hao, Yi; Macara, Ian G (2008) Regulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1. J Cell Biol 182:827-36
Dorfman, Julia; Macara, Ian G (2008) STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7. Mol Biol Cell 19:1614-26

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