Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM050915-04
Application #
2189112
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1994-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Biochemistry
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
De, Mithu; Oleskie, Austin N; Ayyash, Mariam et al. (2017) The Vps13p-Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion. J Cell Biol 216:425-439
De, Mithu; Abazeed, Mohamed E; Fuller, Robert S (2013) Direct binding of the Kex2p cytosolic tail to the VHS domain of yeast Gga2p facilitates TGN to prevacuolar compartment transport and is regulated by phosphorylation. Mol Biol Cell 24:495-509
Komiyama, Tomoko; Coppola, Julia M; Larsen, Martha J et al. (2009) Inhibition of furin/proprotein convertase-catalyzed surface and intracellular processing by small molecules. J Biol Chem 284:15729-38
Abazeed, Mohamed E; Fuller, Robert S (2008) Yeast Golgi-localized, gamma-Ear-containing, ADP-ribosylation factor-binding proteins are but adaptor protein-1 is not required for cell-free transport of membrane proteins from the trans-Golgi network to the prevacuolar compartment. Mol Biol Cell 19:4826-36
Brace, E J; Parkinson, Leah P; Fuller, Robert S (2006) Skp1p regulates Soi3p/Rav1p association with endosomal membranes but is not required for vacuolar ATPase assembly. Eukaryot Cell 5:2104-13
Abazeed, Mohamed E; Blanchette, Jennifer M; Fuller, Robert S (2005) Cell-free transport from the trans-golgi network to late endosome requires factors involved in formation and consumption of clathrin-coated vesicles. J Biol Chem 280:4442-50
Blanchette, Jennifer M; Abazeed, Mohamed E; Fuller, Robert S (2004) Cell-free reconstitution of transport from the trans-golgi network to the late endosome/prevacuolar compartment. J Biol Chem 279:48767-73
Sipos, Gyorgy; Brickner, Jason H; Brace, E J et al. (2004) Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteins. Mol Biol Cell 15:3196-209
Sipos, Gyorgy; Fuller, Robert S (2002) Separation of Golgi and endosomal compartments. Methods Enzymol 351:351-65
MacLeod, K J; Fuller, R S; Scholten, J D et al. (2001) Conserved cysteine and tryptophan residues of the endothelin-converting enzyme-1 CXAW motif are critical for protein maturation and enzyme activity. J Biol Chem 276:30608-14

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