Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM051186-01S1
Application #
2189530
Study Section
Genetics Study Section (GEN)
Project Start
1994-08-01
Project End
1999-07-31
Budget Start
1994-08-01
Budget End
1995-07-31
Support Year
1
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109
Kohlmaier, A; Fassnacht, C; Jin, Y et al. (2015) Src kinase function controls progenitor cell pools during regeneration and tumor onset in the Drosophila intestine. Oncogene 34:2371-84
Patel, Parthive H; Dutta, Devanjali; Edgar, Bruce A (2015) Niche appropriation by Drosophila intestinal stem cell tumours. Nat Cell Biol 17:1182-92
Doumpas, Nikolaos; Ruiz-Romero, Marina; Blanco, Enrique et al. (2013) Brk regulates wing disc growth in part via repression of Myc expression. EMBO Rep 14:261-8
Zielke, Norman; Edgar, Bruce A; DePamphilis, Melvin L (2013) Endoreplication. Cold Spring Harb Perspect Biol 5:a012948
Edgar, Bruce A (2012) Intestinal stem cells: no longer immortal but ever so clever.... EMBO J 31:2441-3
Jiang, Huaqi; Edgar, Bruce A (2012) Intestinal stem cell function in Drosophila and mice. Curr Opin Genet Dev 22:354-60
Zielke, Norman; Kim, Kerry J; Tran, Vuong et al. (2011) Control of Drosophila endocycles by E2F and CRL4(CDT2). Nature 480:123-7
O'Keefe, David D; Edgar, Bruce A; Saucedo, Leslie J (2011) EndoGI modulates Notch signaling and axon guidance in Drosophila. Mech Dev 128:59-70
Jiang, Huaqi; Grenley, Marc O; Bravo, Maria-Jose et al. (2011) EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila. Cell Stem Cell 8:84-95
Jiang, Huaqi; Edgar, Bruce A (2009) EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors. Development 136:483-93

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