Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM051586-03
Application #
2190217
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1994-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Biochemistry
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Liu, Meng-Xi; Jin, Lei; Sun, Si-Jia et al. (2018) Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma. Oncogene 37:1637-1653
Chen, Lei-Lei; Lin, Huai-Peng; Zhou, Wen-Jie et al. (2018) SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response. Cell Rep 25:1485-1500.e4
Han, Han; Qi, Ruxi; Zhou, Jeff Jiajing et al. (2018) Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction. Mol Cell 72:328-340.e8
Meng, Zhipeng; Qiu, Yunjiang; Lin, Kimberly C et al. (2018) RAP2 mediates mechanoresponses of the Hippo pathway. Nature 560:655-660
Ma, Shenghong; Guan, Kun-Liang (2018) Polycystic kidney disease: a Hippo connection. Genes Dev 32:737-739
Ye, Dan; Guan, Kun-Liang; Xiong, Yue (2018) Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates. Trends Cancer 4:151-165
Plouffe, Steven W; Lin, Kimberly C; Moore 3rd, Jerrell L et al. (2018) The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell. J Biol Chem 293:11230-11240
Ma, Xi; Zhang, Shen; He, Long et al. (2017) MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy. Autophagy 13:592-607
Hong, Audrey W; Meng, Zhipeng; Yuan, Hai-Xin et al. (2017) Osmotic stress-induced phosphorylation by NLK at Ser128 activates YAP. EMBO Rep 18:72-86
Lin, Kimberly C; Park, Hyun Woo; Guan, Kun-Liang (2017) Regulation of the Hippo Pathway Transcription Factor TEAD. Trends Biochem Sci 42:862-872

Showing the most recent 10 out of 76 publications