Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM051610-01A2
Application #
2190263
Study Section
Special Emphasis Panel (ZRG5-MBC-1 (02))
Project Start
1996-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Uehara, Tsuyoshi; Park, James T (2008) Growth of Escherichia coli: significance of peptidoglycan degradation during elongation and septation. J Bacteriol 190:3914-22
Uehara, Tsuyoshi; Park, James T (2007) An anhydro-N-acetylmuramyl-L-alanine amidase with broad specificity tethered to the outer membrane of Escherichia coli. J Bacteriol 189:5634-41
Uehara, Tsuyoshi; Suefuji, Kyoko; Jaeger, Tina et al. (2006) MurQ Etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall. J Bacteriol 188:1660-2
Uehara, Tsuyoshi; Suefuji, Kyoko; Valbuena, Noelia et al. (2005) Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine-phosphate. J Bacteriol 187:3643-9
Uehara, Tsuyoshi; Park, James T (2004) The N-acetyl-D-glucosamine kinase of Escherichia coli and its role in murein recycling. J Bacteriol 186:7273-9
Uehara, Tsuyoshi; Park, James T (2003) Identification of MpaA, an amidase in Escherichia coli that hydrolyzes the gamma-D-glutamyl-meso-diaminopimelate bond in murein peptides. J Bacteriol 185:679-82
Uehara, Tsuyoshi; Park, James T (2002) Role of the murein precursor UDP-N-acetylmuramyl-L-Ala-gamma-D-Glu-meso-diaminopimelic acid-D-Ala-D-Ala in repression of beta-lactamase induction in cell division mutants. J Bacteriol 184:4233-9
Cheng, Qiaomei; Park, James T (2002) Substrate specificity of the AmpG permease required for recycling of cell wall anhydro-muropeptides. J Bacteriol 184:6434-6
Park, J T (2001) Identification of a dedicated recycling pathway for anhydro-N-acetylmuramic acid and N-acetylglucosamine derived from Escherichia coli cell wall murein. J Bacteriol 183:3842-7
Cheng, Q; Li, H; Merdek, K et al. (2000) Molecular characterization of the beta-N-acetylglucosaminidase of Escherichia coli and its role in cell wall recycling. J Bacteriol 182:4836-40

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