Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM052593-02
Application #
2191684
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1995-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Hildreth, A Elizabeth; Arndt, Karen M (2017) A transcriptional switch controls meiosis. Elife 6:
Van Oss, S Branden; Cucinotta, Christine E; Arndt, Karen M (2017) Emerging Insights into the Roles of the Paf1 Complex in Gene Regulation. Trends Biochem Sci 42:788-798
Raupach, Elizabeth A; Martens, Joseph A; Arndt, Karen M (2016) Evidence for Regulation of ECM3 Expression by Methylation of Histone H3 Lysine 4 and Intergenic Transcription in Saccharomyces cerevisiae. G3 (Bethesda) 6:2971-81
Van Oss, S Branden; Shirra, Margaret K; Bataille, Alain R et al. (2016) The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6. Mol Cell 64:815-825
Cucinotta, Christine E; Arndt, Karen M (2016) SnapShot: Transcription Elongation. Cell 166:1058-1058.e1
Arndt, Karen M; Reines, Daniel (2015) Termination of Transcription of Short Noncoding RNAs by RNA Polymerase II. Annu Rev Biochem 84:381-404
Cucinotta, Christine E; Young, Alexandria N; Klucevsek, Kristin M et al. (2015) The Nucleosome Acidic Patch Regulates the H2B K123 Monoubiquitylation Cascade and Transcription Elongation in Saccharomyces cerevisiae. PLoS Genet 11:e1005420
Tomson, Brett N; Crisucci, Elia M; Heisler, Lawrence E et al. (2013) Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation. Mol Cell Biol 33:170-82
Mayekar, Manasi K; Gardner, Richard G; Arndt, Karen M (2013) The recruitment of the Saccharomyces cerevisiae Paf1 complex to active genes requires a domain of Rtf1 that directly interacts with the Spt4-Spt5 complex. Mol Cell Biol 33:3259-73
Wier, Adam D; Mayekar, Manasi K; Héroux, Annie et al. (2013) Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proc Natl Acad Sci U S A 110:17290-5

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