Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM052703-02
Application #
2191823
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1995-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Whitehead Institute for Biomedical Research
Department
Type
DUNS #
076580745
City
Cambridge
State
MA
Country
United States
Zip Code
02142
Shin, Jennifer H; Tam, Barney K; Brau, Ricardo R et al. (2007) Force of an actin spring. Biophys J 92:3729-33
Shin, J H; Gardel, M L; Mahadevan, L et al. (2004) Relating microstructure to rheology of a bundled and cross-linked F-actin network in vitro. Proc Natl Acad Sci U S A 101:9636-41
Gardel, M L; Shin, J H; MacKintosh, F C et al. (2004) Elastic behavior of cross-linked and bundled actin networks. Science 304:1301-5
Shin, Jennifer H; Mahadevan, L; So, P T et al. (2004) Bending stiffness of a crystalline actin bundle. J Mol Biol 337:255-61
Shin, Jennifer H; Mahadevan, L; Waller, Guillermina S et al. (2003) Stored elastic energy powers the 60-microm extension of the Limulus polyphemus sperm actin bundle. J Cell Biol 162:1183-8
Choe, S E; Li, L; Matsudaira, P T et al. (2000) Differential stabilization of two hydrophobic cores in the transition state of the villin 14T folding reaction. J Mol Biol 304:99-115
Mahadevan, L; Matsudaira, P (2000) Motility powered by supramolecular springs and ratchets. Science 288:95-100
Schmid, M F; Sherman, M B; Matsudaira, P et al. (1999) Scaling structure factor amplitudes in electron cryomicroscopy using X-Ray solution scattering. J Struct Biol 128:51-7
Sherman, M B; Jakana, J; Sun, S et al. (1999) The three-dimensional structure of the Limulus acrosomal process: a dynamic actin bundle. J Mol Biol 294:139-49
Choe, S E; Matsudaira, P T; Osterhout, J et al. (1998) Folding kinetics of villin 14T, a protein domain with a central beta-sheet and two hydrophobic cores. Biochemistry 37:14508-18

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