Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM054198-01
Application #
2193589
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1996-05-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Berkeley
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Nguyen, Thi Hoang Duong; Tam, Jane; Wu, Robert A et al. (2018) Cryo-EM structure of substrate-bound human telomerase holoenzyme. Nature 557:190-195
Wu, Robert Alexander; Tam, Jane; Collins, Kathleen (2017) DNA-binding determinants and cellular thresholds for human telomerase repeat addition processivity. EMBO J 36:1908-1927
Chiba, Kunitoshi; Vogan, Jacob M; Wu, Robert A et al. (2017) Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo. Mol Cell Biol 37:
Upton, Heather E; Chan, Henry; Feigon, Juli et al. (2017) Shared Subunits of Tetrahymena Telomerase Holoenzyme and Replication Protein A Have Different Functions in Different Cellular Complexes. J Biol Chem 292:217-228
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Farley, Brian M; Collins, Kathleen (2017) Transgenerational function of Tetrahymena Piwi protein Twi8p at distinctive noncoding RNA loci. RNA 23:530-545
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Jiang, Jiansen; Chan, Henry; Cash, Darian D et al. (2015) Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science 350:aab4070
Wan, Bingbing; Tang, Ting; Upton, Heather et al. (2015) The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex. Nat Struct Mol Biol 22:1023-6
Upton, Heather E; Hong, Kyungah; Collins, Kathleen (2014) Direct single-stranded DNA binding by Teb1 mediates the recruitment of Tetrahymena thermophila telomerase to telomeres. Mol Cell Biol 34:4200-12

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