Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM054811-01
Application #
2194137
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1996-08-01
Project End
2001-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Stanford University
Department
Pathology
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Torres, Jorge Z; Summers, Matthew K; Peterson, David et al. (2011) The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly. Cell 147:1309-23
Torres, Jorge Z; Ban, Kenneth H; Jackson, Peter K (2010) A specific form of phospho protein phosphatase 2 regulates anaphase-promoting complex/cyclosome association with spindle poles. Mol Biol Cell 21:897-904
Torres, Jorge Z; Miller, Julie J; Jackson, Peter K (2009) High-throughput generation of tagged stable cell lines for proteomic analysis. Proteomics 9:2888-91
Summers, Matthew K; Pan, Borlan; Mukhyala, Kiran et al. (2008) The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC. Mol Cell 31:544-56
Keck, Jamie M; Summers, Matthew K; Tedesco, Donato et al. (2007) Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). J Cell Biol 178:371-85
Verschuren, Emmy W; Ban, Kenneth H; Masek, Marilyn A et al. (2007) Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence. Mol Cell Biol 27:7955-65
Nachury, Maxence V; Loktev, Alexander V; Zhang, Qihong et al. (2007) A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell 129:1201-13
Eldridge, Adam G; Loktev, Alexander V; Hansen, David V et al. (2006) The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1. Cell 124:367-80
Hansen, David V; Tung, Jeffrey J; Jackson, Peter K (2006) CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit. Proc Natl Acad Sci U S A 103:608-13
Miller, Julie J; Summers, Matthew K; Hansen, David V et al. (2006) Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor. Genes Dev 20:2410-20

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