Sansó, Miriam; Fisher, Robert P (2013) Pause, play, repeat: CDKs push RNAP II's buttons. Transcription 4:146-52
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Schachter, Miriam Merzel; Merrick, Karl A; Larochelle, Stephane et al. (2013) A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression. Mol Cell 50:250-60
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Sansó, Miriam; Fisher, Robert P (2013) Modelling the CDK-dependent transcription cycle in fission yeast. Biochem Soc Trans 41:1660-5
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Horiuchi, Dai; Huskey, Noelle E; Kusdra, Leonard et al. (2012) Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways. Proc Natl Acad Sci U S A 109:E1019-27
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Wohlbold, Lara; Merrick, Karl A; De, Saurav et al. (2012) Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells. PLoS Genet 8:e1002935
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St Amour, Courtney V; Sanso, Miriam; Bosken, Christian A et al. (2012) Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition. Mol Cell Biol 32:2372-83
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Merrick, Karl A; Fisher, Robert P (2012) Why minimal is not optimal: driving the mammalian cell cycle--and drug discovery--with a physiologic CDK control network. Cell Cycle 11:2600-5
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Larochelle, Stéphane; Amat, Ramon; Glover-Cutter, Kira et al. (2012) Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II. Nat Struct Mol Biol 19:1108-15
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Merrick, Karl A; Wohlbold, Lara; Zhang, Chao et al. (2011) Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation. Mol Cell 42:624-36
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Merrick, Karl A; Fisher, Robert P (2010) Putting one step before the other: distinct activation pathways for Cdk1 and Cdk2 bring order to the mammalian cell cycle. Cell Cycle 9:706-14
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