Abstract

Dr. Johnson's long range goal is to understand the cellular and molecular basis of growth control mechanisms that act to establish latent melanocyte precursors or melanocytes in the embryo, maintain these latent precursors in quiescent state for indefinite periods, and recruit them to differentiate at precise developmental stages or in response to cues in regenerating tissues.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM056988-04S1
Application #
6416538
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Program Officer
Greenberg, Judith H
Project Start
1998-01-01
Project End
2002-12-31
Budget Start
2001-03-01
Budget End
2001-12-31
Support Year
4
Fiscal Year
2001
Total Cost
$70,594
Indirect Cost

  Institution

Name
Washington University
Department
Genetics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Herbert, Amy L; Fu, Meng-Meng; Drerup, Catherine M et al. (2017) Dynein/dynactin is necessary for anterograde transport of Mbp mRNA in oligodendrocytes and for myelination in vivo. Proc Natl Acad Sci U S A 114:E9153-E9162
Dardis, Gabrielle; Tryon, Robert; Ton, Quynh et al. (2017) Cx43 suppresses evx1 expression to regulate joint initiation in the regenerating fin. Dev Dyn 246:691-699
Sanchez, Nicholas E; Harty, Breanne L; O'Reilly-Pol, Thomas et al. (2017) Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue. G3 (Bethesda) 7:3415-3425
Enright, Jennifer M; Toomey, Matthew B; Sato, Shin-ya et al. (2015) Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2. Curr Biol 25:3048-57
Zeng, Zhiqiang; Johnson, Stephen L; Lister, James A et al. (2015) Temperature-sensitive splicing of mitfa by an intron mutation in zebrafish. Pigment Cell Melanoma Res 28:229-32
Lee, Hyung Joo; Lowdon, Rebecca F; Maricque, Brett et al. (2015) Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos. Nat Commun 6:6315
Cox, Jane A; LaMora, Angela; Johnson, Stephen L et al. (2014) Novel role for carbamoyl phosphate synthetase 2 in cranial sensory circuit formation. Int J Dev Neurosci 33:41-8
Cho, Kevin; Mahieu, Nathaniel G; Johnson, Stephen L et al. (2014) After the feature presentation: technologies bridging untargeted metabolomics and biology. Curr Opin Biotechnol 28:143-8
Bonchak, Jonathan G; Eby, Jonathan M; Willenborg, Kristin A et al. (2014) Targeting melanocyte and melanoma stem cells by 8-hydroxy-2-dipropylaminotetralin. Arch Biochem Biophys 563:71-8
Tryon, Robert C; Johnson, Stephen L (2014) Clonal analysis of kit ligand a functional expression reveals lineage-specific competence to promote melanocyte rescue in the mutant regenerating caudal fin. PLoS One 9:e102317

Showing the most recent 10 out of 59 publications