Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM058406-04
Application #
6363292
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Program Officer
Deatherage, James F
Project Start
1998-03-01
Project End
2003-02-28
Budget Start
2001-03-01
Budget End
2002-02-28
Support Year
4
Fiscal Year
2001
Total Cost
$208,834
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Genetics
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655
Dutta, Shubham; Mana-Capelli, Sebastian; Paramasivam, Murugan et al. (2018) TRIP6 inhibits Hippo signaling in response to tension at adherens junctions. EMBO Rep 19:337-350
Mana-Capelli, Sebastian; McCollum, Dannel (2018) Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling. J Biol Chem 293:18230-18241
Gupta, Sneha; Govindaraghavan, Meera; McCollum, Dannel (2014) Cross talk between NDR kinase pathways coordinates cytokinesis with cell separation in Schizosaccharomyces pombe. Eukaryot Cell 13:1104-12
Li, Qi; Li, Shuangxi; Mana-Capelli, Sebastian et al. (2014) The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila. Dev Cell 31:291-304
Mana-Capelli, Sebastian; Paramasivam, Murugan; Dutta, Shubham et al. (2014) Angiomotins link F-actin architecture to Hippo pathway signaling. Mol Biol Cell 25:1676-85
Gupta, Sneha; Mana-Capelli, Sebastian; McLean, Janel R et al. (2013) Identification of SIN pathway targets reveals mechanisms of crosstalk between NDR kinase pathways. Curr Biol 23:333-8
Bajpai, Archana; Feoktistova, Anna; Chen, Jun-Song et al. (2013) Dynamics of SIN asymmetry establishment. PLoS Comput Biol 9:e1003147
Cipak, Lubos; Gupta, Sneha; Rajovic, Iva et al. (2013) Crosstalk between casein kinase II and Ste20-related kinase Nak1. Cell Cycle 12:884-8
Johnson, Alyssa E; McCollum, Dannel; Gould, Kathleen L (2012) Polar opposites: Fine-tuning cytokinesis through SIN asymmetry. Cytoskeleton (Hoboken) 69:686-99
Mana-Capelli, Sebastian; McLean, Janel R; Chen, Chun-Ti et al. (2012) The kinesin-14 Klp2 is negatively regulated by the SIN for proper spindle elongation and telophase nuclear positioning. Mol Biol Cell 23:4592-600

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