Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM058595-06
Application #
6773827
Study Section
Allergy and Immunology Study Section (ALY)
Program Officer
Rhoades, Marcus M
Project Start
1999-01-01
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
6
Fiscal Year
2004
Total Cost
$332,200
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Microbiology/Immun/Virology
Type
Other Domestic Higher Education
DUNS #
800772139
City
Houston
State
TX
Country
United States
Zip Code
77030
Goetz, Alexandra E; Wilkinson, Miles (2017) Stress and the nonsense-mediated RNA decay pathway. Cell Mol Life Sci 74:3509-3531
Jones, Samantha H; Wilkinson, Miles (2017) RNA decay, evolution, and the testis. RNA Biol 14:146-155
Borgmann, Jennifer; Tüttelmann, Frank; Dworniczak, Bernd et al. (2016) The human RHOX gene cluster: target genes and functional analysis of gene variants in infertile men. Hum Mol Genet :
Lasalde, Clarivel; Rivera, Andrea V; León, Alfredo J et al. (2014) Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1. Nucleic Acids Res 42:1916-29
Lou, Chih H; Shao, Ada; Shum, Eleen Y et al. (2014) Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway. Cell Rep 6:748-64
Nguyen, Lam Son; Wilkinson, Miles F; Gecz, Jozef (2014) Nonsense-mediated mRNA decay: inter-individual variability and human disease. Neurosci Biobehav Rev 46 Pt 2:175-86
Liu, Chen; Karam, Rachid; Zhou, YingQi et al. (2014) The UPF1 RNA surveillance gene is commonly mutated in pancreatic adenosquamous carcinoma. Nat Med 20:596-8
Karam, Rachid; Wengrod, Jordan; Gardner, Lawrence B et al. (2013) Regulation of nonsense-mediated mRNA decay: implications for physiology and disease. Biochim Biophys Acta 1829:624-33
Ramaiah, Madhuvanthi; Shum, Eleen Y; Wilkinson, Miles F (2012) How to activate a gene: decap its associated noncoding RNA. Mol Cell 45:271-3
Karam, Rachid; Wilkinson, Miles (2012) A conserved microRNA/NMD regulatory circuit controls gene expression. RNA Biol 9:22-6

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