Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM059323-04
Application #
6628830
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Program Officer
Chin, Jean
Project Start
2000-02-01
Project End
2005-03-31
Budget Start
2003-08-01
Budget End
2005-03-31
Support Year
4
Fiscal Year
2003
Total Cost
$227,036
Indirect Cost
Name
Cornell University
Department
Microbiology/Immun/Virology
Type
Schools of Earth Sciences/Natur
DUNS #
872612445
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Chandrangsu, Pete; Loi, Vu Van; Antelmann, Haike et al. (2018) The Role of Bacillithiol in Gram-Positive Firmicutes. Antioxid Redox Signal 28:445-462
Chandrangsu, Pete; Rensing, Christopher; Helmann, John D (2017) Metal homeostasis and resistance in bacteria. Nat Rev Microbiol 15:338-350
Pi, Hualiang; Helmann, John D (2017) Ferrous iron efflux systems in bacteria. Metallomics 9:840-851
Makthal, Nishanth; Nguyen, Kimberly; Do, Hackwon et al. (2017) A Critical Role of Zinc Importer AdcABC in Group A Streptococcus-Host Interactions During Infection and Its Implications for Vaccine Development. EBioMedicine 21:131-141
VanderWal, Arica R; Makthal, Nishanth; Pinochet-Barros, Azul et al. (2017) Iron Efflux by PmtA Is Critical for Oxidative Stress Resistance and Contributes Significantly to Group A Streptococcus Virulence. Infect Immun 85:
Huang, Xiaojuan; Shin, Jung-Ho; Pinochet-Barros, Azul et al. (2017) Bacillus subtilis MntR coordinates the transcriptional regulation of manganese uptake and efflux systems. Mol Microbiol 103:253-268
Shin, Jung-Ho; Helmann, John D (2016) Molecular logic of the Zur-regulated zinc deprivation response in Bacillus subtilis. Nat Commun 7:12612
Pi, Hualiang; Patel, Sarju J; Argüello, José M et al. (2016) The Listeria monocytogenes Fur-regulated virulence protein FrvA is an Fe(II) efflux P1B4 -type ATPase. Mol Microbiol 100:1066-79
Chandrangsu, Pete; Helmann, John D (2016) Intracellular Zn(II) Intoxication Leads to Dysregulation of the PerR Regulon Resulting in Heme Toxicity in Bacillus subtilis. PLoS Genet 12:e1006515
Price, Ian R; Gaballa, Ahmed; Ding, Fang et al. (2015) Mn(2+)-sensing mechanisms of yybP-ykoY orphan riboswitches. Mol Cell 57:1110-1123

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