We propose computational approaches aiding automated compilation of molecular networks from research literature, cleansing of the resulting database, and assessing reliability of facts stored in the database.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM061372-05
Application #
6923756
Study Section
Genome Study Section (GNM)
Program Officer
Anderson, James J
Project Start
2001-08-01
Project End
2006-09-29
Budget Start
2005-08-01
Budget End
2006-09-29
Support Year
5
Fiscal Year
2005
Total Cost
$395,905
Indirect Cost
Name
Columbia University (N.Y.)
Department
Genetics
Type
Schools of Medicine
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Yao, Lixia; Li, Ying; Ghosh, Soumitra et al. (2015) Health ROI as a measure of misalignment of biomedical needs and resources. Nat Biotechnol 33:807-11
Soldatova, Larisa N; Rzhetsky, Andrey; De Grave, Kurt et al. (2013) Representation of probabilistic scientific knowledge. J Biomed Semantics 4 Suppl 1:S7
Divoli, Anna; Mendonça, Eneida A; Evans, James A et al. (2011) Conflicting biomedical assumptions for mathematical modeling: the case of cancer metastasis. PLoS Comput Biol 7:e1002132
Balkir, Atilla Soner; Foster, Ian; Rzhetsky, Andrey (2011) A Distributed Look-up Architecture for Text Mining Applications using MapReduce. Proc Int Symp High Perform Distrib Comput 2011:
Evans, James A; Rzhetsky, Andrey (2011) Advancing science through mining libraries, ontologies, and communities. J Biol Chem 286:23659-66
Yao, Lixia; Divoli, Anna; Mayzus, Ilya et al. (2011) Benchmarking ontologies: bigger or better? PLoS Comput Biol 7:e1001055
Yao, Lixia; Evans, James A; Rzhetsky, Andrey (2010) Novel opportunities for computational biology and sociology in drug discovery. Trends Biotechnol 28:161-70
Evans, James; Rzhetsky, Andrey (2010) Philosophy of science. Machine science. Science 329:399-400
Yao, Lixia; Evans, James A; Rzhetsky, Andrey (2009) Novel opportunities for computational biology and sociology in drug discovery. Trends Biotechnol 27:531-40
Iossifov, Ivan; Rodriguez-Esteban, Raul; Mayzus, Ilya et al. (2009) Looking at cerebellar malformations through text-mined interactomes of mice and humans. PLoS Comput Biol 5:e1000559

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