Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD009020-21
Application #
2196647
Study Section
Endocrinology Study Section (END)
Project Start
1978-05-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
21
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Physiology
Type
Schools of Medicine
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Ng, Lily; Lyubarsky, Arkady; Nikonov, Sergei S et al. (2010) Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors. J Neurosci 30:3347-57
Ng, Lily; Hernandez, Arturo; He, Wenxuan et al. (2009) A protective role for type 3 deiodinase, a thyroid hormone-inactivating enzyme, in cochlear development and auditory function. Endocrinology 150:1952-60
Galton, Valerie Anne; Schneider, Mark J; Clark, Ann S et al. (2009) Life without thyroxine to 3,5,3'-triiodothyronine conversion: studies in mice devoid of the 5'-deiodinases. Endocrinology 150:2957-63
St Germain, Donald L; Galton, Valerie Anne; Hernandez, Arturo (2009) Minireview: Defining the roles of the iodothyronine deiodinases: current concepts and challenges. Endocrinology 150:1097-107
Galton, Valerie Anne; Wood, Emily T; St Germain, Emily A et al. (2007) Thyroid hormone homeostasis and action in the type 2 deiodinase-deficient rodent brain during development. Endocrinology 148:3080-8
Schneider, Mark J; Fiering, Steven N; Thai, B et al. (2006) Targeted disruption of the type 1 selenodeiodinase gene (Dio1) results in marked changes in thyroid hormone economy in mice. Endocrinology 147:580-9
Galton, Valerie Anne (2005) The roles of the iodothyronine deiodinases in mammalian development. Thyroid 15:823-34
St Germain, Donald L; Hernandez, Arturo; Schneider, Mark J et al. (2005) Insights into the role of deiodinases from studies of genetically modified animals. Thyroid 15:905-16
Ng, Lily; Goodyear, Richard J; Woods, Chad A et al. (2004) Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase. Proc Natl Acad Sci U S A 101:3474-9
Wasco, Emily C; Martinez, Elena; Grant, Katherine S et al. (2003) Determinants of iodothyronine deiodinase activities in rodent uterus. Endocrinology 144:4253-61

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