Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD011489-19
Application #
2196820
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1991-01-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Burger, Laura L; Haisenleder, Daniel J; Aylor, Kevin W et al. (2008) Regulation of intracellular signaling cascades by GNRH pulse frequency in the rat pituitary: roles for CaMK II, ERK, and JNK activation. Biol Reprod 79:947-53
Haisenleder, D J; Burger, L L; Walsh, H E et al. (2008) Pulsatile gonadotropin-releasing hormone stimulation of gonadotropin subunit transcription in rat pituitaries: evidence for the involvement of Jun N-terminal kinase but not p38. Endocrinology 149:139-45
Burger, Laura L; Haisenleder, Daniel J; Wotton, Gordon M et al. (2007) The regulation of FSHbeta transcription by gonadal steroids: testosterone and estradiol modulation of the activin intracellular signaling pathway. Am J Physiol Endocrinol Metab 293:E277-85
Haisenleder, Daniel J; Aylor, Kevin W; Burger, Laura L et al. (2006) Stimulation of FSHbeta transcription by blockade of endogenous pituitary follistatin production: Efficacy of adenoviral-delivered antisense RNA in the rat. Endocrine 29:399-404
Haisenleder, D J; Burger, L L; Aylor, K W et al. (2005) Testosterone stimulates follicle-stimulating hormone beta transcription via activation of extracellular signal-regulated kinase: evidence in rat pituitary cells. Biol Reprod 72:523-9
Prendergast, Kathleen A; Burger, Laura L; Aylor, Kevin W et al. (2004) Pituitary follistatin gene expression in female rats: evidence that inhibin regulates transcription. Biol Reprod 70:364-70
Burger, Laura L; Haisenleder, Daniel J; Aylor, Kevin W et al. (2004) Regulation of luteinizing hormone-beta and follicle-stimulating hormone (FSH)-beta gene transcription by androgens: testosterone directly stimulates FSH-beta transcription independent from its role on follistatin gene expression. Endocrinology 145:71-8
Burger, L L; Haisenleder, D J; Dalkin, A C et al. (2004) Regulation of gonadotropin subunit gene transcription. J Mol Endocrinol 33:559-84
Haisenleder, D J; Burger, L L; Aylor, K W et al. (2003) Gonadotropin-releasing hormone stimulation of gonadotropin subunit transcription: evidence for the involvement of calcium/calmodulin-dependent kinase II (Ca/CAMK II) activation in rat pituitaries. Endocrinology 144:2768-74
Burger, Laura L; Dalkin, Alan C; Aylor, Kevin W et al. (2002) GnRH pulse frequency modulation of gonadotropin subunit gene transcription in normal gonadotropes-assessment by primary transcript assay provides evidence for roles of GnRH and follistatin. Endocrinology 143:3243-9

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