Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD016272-15
Application #
2197292
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1981-09-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Dumesic, Daniel A; Richards, Joanne S (2013) Ontogeny of the ovary in polycystic ovary syndrome. Fertil Steril 100:23-38
Liu, Zhilin; Castrillon, Diego H; Zhou, Wei et al. (2013) FOXO1/3 depletion in granulosa cells alters follicle growth, death and regulation of pituitary FSH. Mol Endocrinol 27:238-52
Richards, J S; Fan, H-Y; Liu, Z et al. (2012) Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis. Oncogene 31:1504-20
Richards, JoAnne S; Liu, Zhilin; Kawai, Tomoko et al. (2012) Adiponectin and its receptors modulate granulosa cell and cumulus cell functions, fertility, and early embryo development in the mouse and human. Fertil Steril 98:471-9.e1
Boerboom, Derek; Lafond, Jean-François; Zheng, Xiaofeng et al. (2011) Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla. Dev Dyn 240:1806-14
Richards, Joanne S; Pangas, Stephanie A (2010) New insights into ovarian function. Handb Exp Pharmacol :3-27
Richards, Joanne S; Pangas, Stephanie A (2010) The ovary: basic biology and clinical implications. J Clin Invest 120:963-72
Boyer, Alexandre; Lapointe, Evelyne; Zheng, Xiaofeng et al. (2010) WNT4 is required for normal ovarian follicle development and female fertility. FASEB J 24:3010-25
Fan, Heng-Yu; Liu, Zhilin; Paquet, Marilene et al. (2009) Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells. Cancer Res 69:6463-72
Fan, Heng-Yu; Liu, Zhilin; Cahill, Nicola et al. (2008) Targeted disruption of Pten in ovarian granulosa cells enhances ovulation and extends the life span of luteal cells. Mol Endocrinol 22:2128-40

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