Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
2R01HD017332-09A5
Application #
2197422
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1983-04-01
Project End
2001-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Chicago
Department
Pediatrics
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Cortes, Mauricio; Cortes, Leslie K; Schwartz, Nancy B (2015) Mapping proteoglycan functions with glycosidases. Methods Mol Biol 1229:443-55
Lauing, Kristen L; Cortes, Mauricio; Domowicz, Miriam S et al. (2014) Aggrecan is required for growth plate cytoarchitecture and differentiation. Dev Biol 396:224-36
Schwartz, Nancy B; Domowicz, Miriam S (2014) Chemistry and function of glycosaminoglycans in the nervous system. Adv Neurobiol 9:89-115
Mis, Emily K; Liem Jr, Karel F; Kong, Yong et al. (2014) Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol 385:67-82
Bradley, Michael E; Rest, Joshua S; Li, Wen-Hsiung et al. (2009) Sulfate activation enzymes: phylogeny and association with pyrophosphatase. J Mol Evol 68:1-13
Domowicz, Miriam S; Cortes, Mauricio; Henry, Judith G et al. (2009) Aggrecan modulation of growth plate morphogenesis. Dev Biol 329:242-57
Pirok 3rd, Edward W; Domowicz, Miriam S; Henry, Judith et al. (2005) APBP-1, a DNA/RNA-binding protein, interacts with the chick aggrecan regulatory region. J Biol Chem 280:35606-16
Singh, Bhawani; Schwartz, Nancy B (2003) Identification and functional characterization of the novel BM-motif in the murine phosphoadenosine phosphosulfate (PAPS) synthetase. J Biol Chem 278:71-5
Kurima, K; Singh, B; Schwartz, N B (1999) Genomic organization of the mouse and human genes encoding the ATP sulfurylase/adenosine 5'-phosphosulfate kinase isoform SK2. J Biol Chem 274:33306-12
Deyrup, A T; Krishnan, S; Singh, B et al. (1999) Activity and stability of recombinant bifunctional rearranged and monofunctional domains of ATP-sulfurylase and adenosine 5'-phosphosulfate kinase. J Biol Chem 274:10751-7

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