Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD018394-12
Application #
2197652
Study Section
Reproductive Biology Study Section (REB)
Project Start
1984-03-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Organized Research Units
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Malcolm, Karl D; Jackson, Leslie M; Bergeon, Christine et al. (2006) Long-term exposure of female sheep to physiologic concentrations of estradiol: effects on the onset and maintenance of reproductive function, pregnancy, and social development in female offspring. Biol Reprod 75:844-52
Smith, G D; Jackson, L M; Foster, D L (2002) Leptin regulation of reproductive function and fertility. Theriogenology 57:73-86
Nagatani, S; Thompson, R C; Foster, D L (2001) Prevention of glucoprivic stimulation of corticosterone secretion by leptin does not restore high frequency luteinizing hormone pulses in rats. J Neuroendocrinol 13:371-7
Nagatani, S; Zeng, Y; Keisler, D H et al. (2000) Leptin regulates pulsatile luteinizing hormone and growth hormone secretion in the sheep. Endocrinology 141:3965-75
Nagatani, S; Guthikonda, P; Foster, D L (2000) Appearance of a nocturnal peak of leptin secretion in the pubertal rat. Horm Behav 37:345-52
Ohkura, S; Tanaka, T; Nagatani, S et al. (2000) Central, but not peripheral, glucose-sensing mechanisms mediate glucoprivic suppression of pulsatile luteinizing hormone secretion in the sheep. Endocrinology 141:4472-80
Bucholtz, D C; Chiesa, A; Pappano, W N et al. (2000) Regulation of pulsatile luteinizing hormone secretion by insulin in the diabetic male lamb. Biol Reprod 62:1248-55
Foster, D L; Nagatani, S (1999) Physiological perspectives on leptin as a regulator of reproduction: role in timing puberty. Biol Reprod 60:205-15
Kim, S J; Foster, D L; Wood, R I (1999) Prenatal testosterone masculinizes synaptic input to gonadotropin-releasing hormone neurons in sheep. Biol Reprod 61:599-605
Medina, C L; Nagatani, S; Darling, T A et al. (1998) Glucose availability modulates the timing of the luteinizing hormone surge in the ewe. J Neuroendocrinol 10:785-92

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