Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD019089-11
Application #
2197766
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1987-08-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Indiana University-Purdue University at Indianapolis
Department
Pediatrics
Type
Schools of Medicine
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202

  Publications

Shen, Weihua; Wisniowski, Paul; Denne, Scott C et al. (2005) Anabolic effects of insulin and IGF-I in the ovine fetus are reduced by prolonged maternal fasting. Am J Physiol Endocrinol Metab 288:E907-13
Shen, Weihua; Boyle, David W; Liechty, Edward A (2005) Changes in 4E-BP1 and p70S6K phosphorylation in skeletal muscle of the ovine fetus after prolonged maternal fasting: effects of insulin and IGF-I. Pediatr Res 58:833-9
Shen, Wei-Hua; Boyle, David W; Wisniowski, Paul et al. (2005) Insulin and IGF-I stimulate the formation of the eukaryotic initiation factor 4F complex and protein synthesis in C2C12 myotubes independent of availability of external amino acids. J Endocrinol 185:275-89
Shen, Weihua; Wisniowski, Paul; Ahmed, Lasker et al. (2003) Protein anabolic effects of insulin and IGF-I in the ovine fetus. Am J Physiol Endocrinol Metab 284:E748-56
Poindexter, Brenda B; Ehrenkranz, Richard A; Stoll, Barbara J et al. (2003) Effect of parenteral glutamine supplementation on plasma amino acid concentrations in extremely low-birth-weight infants. Am J Clin Nutr 77:737-43
Shen, Weihua; Mallon, Daniel; Boyle, David W et al. (2002) IGF-I and insulin regulate eIF4F formation by different mechanisms in muscle and liver in the ovine fetus. Am J Physiol Endocrinol Metab 283:E593-603
Liechty, E A; Boyle, D W; Moorehead, H et al. (1999) Aromatic amino acids are utilized and protein synthesis is stimulated during amino acid infusion in the ovine fetus. J Nutr 129:1161-6
Liechty, E A; Boyle, D W; Moorehead, H et al. (1999) Glucose and amino acid kinetic response to graded infusion of rhIGF-I in the late gestation ovine fetus. Am J Physiol 277:E537-43
Liechty, E A; Denne, S C (1998) Regulation of fetal amino acid metabolism: substrate or hormonal regulation? J Nutr 128:342S-346S
Ahmed, L S; Moorehead, H; Leitch, C A et al. (1998) Determination of the specific activity of sheep plasma amino acids using high-performance liquid chromatography: comparison study between liquid scintillation counter and on-line flow-through detector. J Chromatogr B Biomed Sci Appl 710:27-35

Showing the most recent 10 out of 19 publications