Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD019837-10
Application #
2197880
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1985-08-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Nebraska Medical Center
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198
Kelly, D L; Rizzino, A (1999) Growth regulatory factors and carcinogenesis: the roles played by transforming growth factor beta, its receptors and signaling pathways. Anticancer Res 19:4791-807
Lamb, K A; Rizzino, A (1998) Effects of differentiation on the transcriptional regulation of the FGF-4 gene: critical roles played by a distal enhancer. Mol Reprod Dev 51:218-24
Lamb, K A; Johnson, L R; Rizzino, A (1997) NF-Y binds to the CCAAT box motif of the FGF-4 gene and promotes FGF-4 expression in embryonal carcinoma cells. Mol Reprod Dev 48:301-9
Wilder, P J; Kelly, D; Brigman, K et al. (1997) Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny. Dev Biol 192:614-29
Wilder, P J; Mountjoy, C; Macleod, M C et al. (1997) DNA sequence and nucleosome placement on the murine fibroblast growth factor-4 gene. DNA Seq 7:117-21
Miller, K; Rizzino, A (1996) Constitutive expression of fibroblast growth factor-4 does not alter the growth or the differentiation of embryonal carcinoma cells. Cell Growth Differ 7:203-11
Scholtz, B; Lamb, K; Rosfjord, E et al. (1996) Appearance of nuclear protease activity after embryonal carcinoma cells undergo differentiation. Dev Biol 173:420-7
Lickteig, K; Lamb, K; Brigman, K et al. (1996) Effects of oxidation and reduction on the binding of transcription factors to cis-regulatory elements located in the FGF-4 gene. Mol Reprod Dev 44:146-52
Scholtz, B; Kingsley-Kallesen, M; Rizzino, A (1996) Transcription of the transforming growth factor-beta2 gene is dependent on an E-box located between an essential cAMP response element/activating transcription factor motif and the TATA box of the gene. J Biol Chem 271:32375-80
Lamb, K; Rosfjord, E; Brigman, K et al. (1996) Binding of transcription factors to widely-separated cis-regulatory elements of the murine FGF-4 gene. Mol Reprod Dev 44:460-71

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