Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD022400-02
Application #
3321906
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1987-01-01
Project End
1989-12-31
Budget Start
1988-01-01
Budget End
1988-12-31
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Barnes, George L; Javed, Amjad; Waller, Sylvan M et al. (2003) Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res 63:2631-7
Barnes, George L; Della Torre, Thomas; Sommer, Beatrice et al. (2002) Transcriptional regulation restricting bone sialoprotein gene expression to both hypertrophic chondrocytes and osteoblasts. J Cell Biochem 87:458-69
Cullinane, Dennis M; Fredrick, Amy; Eisenberg, Solomon R et al. (2002) Induction of a neoarthrosis by precisely controlled motion in an experimental mid-femoral defect. J Orthop Res 20:579-86
Cho, Tae-Joon; Gerstenfeld, Louis C; Einhorn, Thomas A (2002) Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing. J Bone Miner Res 17:513-20
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Javed, A; Barnes, G L; Jasanya, B O et al. (2001) runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins. Mol Cell Biol 21:2891-905
Kon, T; Cho, T J; Aizawa, T et al. (2001) Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing. J Bone Miner Res 16:1004-14
Aizawa, T; Kon, T; Einhorn, T A et al. (2001) Induction of apoptosis in chondrocytes by tumor necrosis factor-alpha. J Orthop Res 19:785-96
Ranger, A M; Gerstenfeld, L C; Wang, J et al. (2000) The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis. J Exp Med 191:22-Sep
Gerstenfeld, L C; Toma, C D; Schaffer, J L et al. (1998) Chondrogenic potential of skeletal cell populations: selective growth of chondrocytes and their morphogenesis and development in vitro. Microsc Res Tech 43:156-73

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